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Cholesterol-dependent cytolysins impair pro-inflammatory macrophage responses

Necrotizing soft tissue infections are lethal polymicrobial infections. Two key microbes that cause necrotizing soft tissue infections are Streptococcus pyogenes and Clostridium perfringens. These pathogens evade innate immunity using multiple virulence factors, including cholesterol-dependent cytol...

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Detalles Bibliográficos
Autores principales:	Bhattacharjee, Pushpak, Keyel, Peter A.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915385/ https://www.ncbi.nlm.nih.gov/pubmed/29691463 http://dx.doi.org/10.1038/s41598-018-24955-2

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