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Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain
Slow brain oscillations are usually coherent over long distances and thought to link distributed cell assemblies. In mice, theta (5–10 Hz) stands as one of the most studied slow rhythms. However, mice often breathe at theta frequency, and we recently reported that nasal respiration leads to local fi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915406/ https://www.ncbi.nlm.nih.gov/pubmed/29691421 http://dx.doi.org/10.1038/s41598-018-24629-z |
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author | Tort, Adriano B. L. Ponsel, Simon Jessberger, Jakob Yanovsky, Yevgenij Brankačk, Jurij Draguhn, Andreas |
author_facet | Tort, Adriano B. L. Ponsel, Simon Jessberger, Jakob Yanovsky, Yevgenij Brankačk, Jurij Draguhn, Andreas |
author_sort | Tort, Adriano B. L. |
collection | PubMed |
description | Slow brain oscillations are usually coherent over long distances and thought to link distributed cell assemblies. In mice, theta (5–10 Hz) stands as one of the most studied slow rhythms. However, mice often breathe at theta frequency, and we recently reported that nasal respiration leads to local field potential (LFP) oscillations that are independent of theta. Namely, we showed respiration-coupled oscillations in the hippocampus, prelimbic cortex, and parietal cortex, suggesting that respiration could impose a global brain rhythm. Here we extend these findings by analyzing LFPs from 15 brain regions recorded simultaneously with respiration during exploration and REM sleep. We find that respiration-coupled oscillations can be detected in parallel with theta in several neocortical regions, from prefrontal to visual areas, and also in subcortical structures such as the thalamus, amygdala and ventral hippocampus. They might have escaped attention in previous studies due to the absence of respiration monitoring, the similarity with theta oscillations, and the highly variable peak frequency. We hypothesize that respiration-coupled oscillations constitute a global brain rhythm suited to entrain distributed networks into a common regime. However, whether their widespread presence reflects local network activity or is due to volume conduction remains to be determined. |
format | Online Article Text |
id | pubmed-5915406 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2018 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-59154062018-04-30 Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain Tort, Adriano B. L. Ponsel, Simon Jessberger, Jakob Yanovsky, Yevgenij Brankačk, Jurij Draguhn, Andreas Sci Rep Article Slow brain oscillations are usually coherent over long distances and thought to link distributed cell assemblies. In mice, theta (5–10 Hz) stands as one of the most studied slow rhythms. However, mice often breathe at theta frequency, and we recently reported that nasal respiration leads to local field potential (LFP) oscillations that are independent of theta. Namely, we showed respiration-coupled oscillations in the hippocampus, prelimbic cortex, and parietal cortex, suggesting that respiration could impose a global brain rhythm. Here we extend these findings by analyzing LFPs from 15 brain regions recorded simultaneously with respiration during exploration and REM sleep. We find that respiration-coupled oscillations can be detected in parallel with theta in several neocortical regions, from prefrontal to visual areas, and also in subcortical structures such as the thalamus, amygdala and ventral hippocampus. They might have escaped attention in previous studies due to the absence of respiration monitoring, the similarity with theta oscillations, and the highly variable peak frequency. We hypothesize that respiration-coupled oscillations constitute a global brain rhythm suited to entrain distributed networks into a common regime. However, whether their widespread presence reflects local network activity or is due to volume conduction remains to be determined. Nature Publishing Group UK 2018-04-24 /pmc/articles/PMC5915406/ /pubmed/29691421 http://dx.doi.org/10.1038/s41598-018-24629-z Text en © The Author(s) 2018 Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/. |
spellingShingle | Article Tort, Adriano B. L. Ponsel, Simon Jessberger, Jakob Yanovsky, Yevgenij Brankačk, Jurij Draguhn, Andreas Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain |
title | Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain |
title_full | Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain |
title_fullStr | Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain |
title_full_unstemmed | Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain |
title_short | Parallel detection of theta and respiration-coupled oscillations throughout the mouse brain |
title_sort | parallel detection of theta and respiration-coupled oscillations throughout the mouse brain |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915406/ https://www.ncbi.nlm.nih.gov/pubmed/29691421 http://dx.doi.org/10.1038/s41598-018-24629-z |
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