Fetal demise and failed antibody therapy during Zika virus infection of pregnant macaques

Zika virus (ZIKV) infection of pregnant women is associated with pathologic complications of fetal development. Here, we infect pregnant rhesus macaques (Macaca mulatta) with a minimally passaged ZIKV isolate from Rio de Janeiro, where a high rate of fetal development complications was observed. The...

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Detalles Bibliográficos
Autores principales: Magnani, Diogo M., Rogers, Thomas F., Maness, Nicholas J., Grubaugh, Nathan D., Beutler, Nathan, Bailey, Varian K., Gonzalez-Nieto, Lucas, Gutman, Martin J., Pedreño-Lopez, Núria, Kwal, Jaclyn M., Ricciardi, Michael J., Myers, Tereance A., Julander, Justin G., Bohm, Rudolf P., Gilbert, Margaret H., Schiro, Faith, Aye, Pyone P., Blair, Robert V., Martins, Mauricio A., Falkenstein, Kathrine P., Kaur, Amitinder, Curry, Christine L., Kallas, Esper G., Desrosiers, Ronald C., Goldschmidt-Clermont, Pascal J., Whitehead, Stephen S., Andersen, Kristian G., Bonaldo, Myrna C., Lackner, Andrew A., Panganiban, Antonito T., Burton, Dennis R., Watkins, David I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915455/
https://www.ncbi.nlm.nih.gov/pubmed/29691387
http://dx.doi.org/10.1038/s41467-018-04056-4

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