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Deoxyribonucleotide Triphosphate Metabolism in Cancer and Metabolic Disease
The maintenance of a healthy deoxyribonucleotide triphosphate (dNTP) pool is critical for the proper replication and repair of both nuclear and mitochondrial DNA. Temporal, spatial, and ratio imbalances of the four dNTPs have been shown to have a mutagenic and cytotoxic effect. It is, therefore, ess...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2018
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915462/ https://www.ncbi.nlm.nih.gov/pubmed/29720963 http://dx.doi.org/10.3389/fendo.2018.00177 |