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Imaging α(v)β(3) integrin expression in skeletal metastases with (99m)Tc-maraciclatide single-photon emission computed tomography: detection and therapy response assessment

PURPOSE: Osteoclast activity is an important factor in the pathogenesis of skeletal metastases and is a potential therapeutic target. This study aimed to determine if selective uptake of (99m)Tc-maraciclatide, a radiopharmaceutical targeting α(v)β(3) integrin, occurs in prostate cancer (PCa) bone me...

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Detalles Bibliográficos
Autores principales:	Cook, Gary J. R., Azad, Gurdip K., Taylor, Benjamin P., Lee, Eugene, Morrison, Matthew S., Hughes, Simon, Morris, Stephen, Rudman, Sarah, Chowdhury, Simon, Goh, Vicky
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915496/ https://www.ncbi.nlm.nih.gov/pubmed/29396636 http://dx.doi.org/10.1007/s00259-017-3926-7

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