Effects of pre-existing orthopoxvirus-specific immunity on the performance of Modified Vaccinia virus Ankara-based influenza vaccines

The replication-deficient orthopoxvirus modified vaccinia virus Ankara (MVA) is a promising vaccine vector against various pathogens and has an excellent safety record. However, pre-existing vector-specific immunity is frequently suggested to be a drawback of MVA-based vaccines. To address this issu...

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Detalles Bibliográficos
Autores principales: Altenburg, Arwen F., van Trierum, Stella E., de Bruin, Erwin, de Meulder, Dennis, van de Sandt, Carolien E., van der Klis, Fiona R. M., Fouchier, Ron A. M., Koopmans, Marion P. G., Rimmelzwaan, Guus F., de Vries, Rory D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915537/
https://www.ncbi.nlm.nih.gov/pubmed/29692427
http://dx.doi.org/10.1038/s41598-018-24820-2

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