Cargando…

Elf3 Contributes to Cartilage Degradation in vivo in a Surgical Model of Post-Traumatic Osteoarthritis

The E-74 like factor 3 (ELF3) is a transcription factor induced by inflammatory factors in various cell types, including chondrocytes. ELF3 levels are elevated in human cartilage from patients with osteoarthritis (OA), and ELF3 contributes to the IL-1β-induced expression of genes encoding Mmp13, Nos...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wondimu, Elisabeth B., Culley, Kirsty L., Quinn, Justin, Chang, Jun, Dragomir, Cecilia L., Plumb, Darren A., Goldring, Mary B., Otero, Miguel
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915581/ https://www.ncbi.nlm.nih.gov/pubmed/29691435 http://dx.doi.org/10.1038/s41598-018-24695-3

Ejemplares similares

Inducible knockout of CHUK/IKKα in adult chondrocytes reduces progression of cartilage degradation in a surgical model of osteoarthritis
por: Culley, Kirsty L., et al.
Publicado: (2019)

Pathophysiology of osteoarthritis: canonical NF-κB/IKKβ-dependent and kinase-independent effects of IKKα in cartilage degradation and chondrocyte differentiation
por: Olivotto, Eleonora, et al.
Publicado: (2015)

Bone and cartilage in osteoarthritis: is what's best for one good or bad for the other?
por: Goldring, Steven R, et al.
Publicado: (2010)

LOXL2 as a protective in osteoarthritis cartilage
por: Bais, Manish V., et al.
Publicado: (2017)

Transcriptomic and epigenomic analyses uncovered Lrrc15 as a contributing factor to cartilage damage in osteoarthritis
por: Singh, Purva, et al.
Publicado: (2021)

Targeting Cartilage Degradation in Osteoarthritis
por: McClurg, Oliver, et al.
Publicado: (2021)

Cross-talk between subchondral bone and articular cartilage in osteoarthritis
por: Goldring, Steven R
Publicado: (2012)

Developmental Mechanisms in Articular Cartilage Degradation in Osteoarthritis
por: Tchetina, Elena V.
Publicado: (2011)

Sulforaphane Represses Matrix-Degrading Proteases and Protects Cartilage From Destruction In Vitro and In Vivo
por: Davidson, Rose K, et al.
Publicado: (2013)

Chondrogenesis, joint formation, and cartilage metabolism
por: Goldring, Mary B
Publicado: (2012)

ELFE at CERN
por: Burkhardt, H
Publicado: (1999)

Soluble biglycan: a potential mediator of cartilage degradation in osteoarthritis
por: Barreto, Goncalo, et al.
Publicado: (2015)

Interleukin-29 Enhances Synovial Inflammation and Cartilage Degradation in Osteoarthritis
por: Xu, Lingxiao, et al.
Publicado: (2016)

Models to define the stages of articular cartilage degradation in osteoarthritis development
por: Poulet, Blandine
Publicado: (2017)

Cartilage homeostasis in health and rheumatic diseases
por: Goldring, Mary B, et al.
Publicado: (2009)

Transcriptional analysis of micro-dissected articular cartilage in post-traumatic murine osteoarthritis
por: Gardiner, M.D., et al.
Publicado: (2015)

CC-Chemokine Receptor-2 Expression in Osteoblasts Contributes to Cartilage and Bone Damage during Post-Traumatic Osteoarthritis
por: Willcockson, Helen, et al.
Publicado: (2023)

CXCL12/CXCR4 Axis Regulates Aggrecanase Activation and Cartilage Degradation in a Post-Traumatic Osteoarthritis Rat Model
por: Lu, Weiwei, et al.
Publicado: (2016)

Mesenchymal stem cell-derived exosomal microRNA-136-5p inhibits chondrocyte degeneration in traumatic osteoarthritis by targeting ELF3
por: Chen, Xue, et al.
Publicado: (2020)

Natural Compounds: Potential Therapeutics for the Inhibition of Cartilage Matrix Degradation in Osteoarthritis
por: Ashruf, Omer S., et al.
Publicado: (2022)

Proteolysis and cartilage development are activated in the synovium after surgical induction of post traumatic osteoarthritis
por: Ayturk, Ugur M., et al.
Publicado: (2020)

Contribution of joint tissue properties to load-induced osteoarthritis
por: Ayobami, Olufunmilayo O., et al.
Publicado: (2022)

The ELFE programme and project
por: Laget, J M
Publicado: (1997)

The Nursery Elf (Poetry)
Publicado: (1881)

Anabolic role of lysyl oxidase like-2 in cartilage of knee and temporomandibular joints with osteoarthritis
por: Alshenibr, Weam, et al.
Publicado: (2017)

ELF MFs: Straif et al. Respond
por: Straif, Kurt, et al.
Publicado: (2005)

Early knee osteoarthritis
por: Favero, Marta, et al.
Publicado: (2015)

Overexpression of cystatin C in synovium does not reduce synovitis or cartilage degradation in established osteoarthritis
por: Kyostio-Moore, Sirkka, et al.
Publicado: (2015)

Transcript Profiling of Elf5(+/−) Mammary Glands during Pregnancy Identifies Novel Targets of Elf5
por: Rogers, Renee L., et al.
Publicado: (2010)

Pathology of the Calcified Zone of Articular Cartilage in Post-Traumatic Osteoarthritis in Rat Knees
por: Schultz, Melissa, et al.
Publicado: (2015)

Evaluation of articular cartilage with quantitative MRI in an equine model of post‐traumatic osteoarthritis
por: Kajabi, Abdul Wahed, et al.
Publicado: (2020)

Fluoxetine ameliorates cartilage degradation in osteoarthritis by inhibiting Wnt/β-catenin signaling
por: Miyamoto, Kentaro, et al.
Publicado: (2017)

Inhibition of fibroblast activation protein ameliorates cartilage matrix degradation and osteoarthritis progression
por: Fan, Aoyuan, et al.
Publicado: (2023)

ELF3, ELF5, EHF and SPDEF Transcription Factors in Tissue Homeostasis and Cancer
por: Luk, Ian Y., et al.
Publicado: (2018)

Cartilage turnover and intra-articular corticosteroid injections in knee osteoarthritis
por: Klocke, Rainer, et al.
Publicado: (2018)

Occupational Carcinogens: ELF MFs
por: Mild, Kjell Hanson, et al.
Publicado: (2005)

ELFE: an electron laboratory for Europe
por: Laget, J M
Publicado: (1995)

From ELF to Compressibility in Solids
por: Contreras-García, Julia, et al.
Publicado: (2015)

THE NATIONAL ELF SERVICE …… NOT THE NHS
por: Spence, Roy
Publicado: (2016)

ELFE at CERN: Conceptual Design Report
por: Aulenbacher, K, et al.
Publicado: (1999)

Cannot write session to /tmp/vufind_sessions/sess_gc7h0u713rup9qe8iskl3b3gft