Mining the Synergistic Core Allosteric Modules Variation and Sequencing Pharmacological Module Drivers in a Preclinical Model of Ischemia

Identifying the variation of core modules and hubs seems to be critical for characterizing variable pharmacological mechanisms based on topological alteration of disease networks. We first identified a total of eight core modules by using an approach of multiple modular characteristic fusing (MMCF)...

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Detalles Bibliográficos
Autores principales: Zhang, Yingying, Zhao, Zide, Yu, Yanan, Liu, Jun, Wang, Pengqian, Li, Bing, Zhang, Xiaoxu, Chen, Yinying, Wang, Zhong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915616/
https://www.ncbi.nlm.nih.gov/pubmed/29464871
http://dx.doi.org/10.1002/psp4.12281

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