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Bioinformatics challenges and perspectives when studying the effect of epigenetic modifications on alternative splicing
It is widely known that epigenetic modifications are important in regulating transcription, but several have also been reported in alternative splicing. The regulation of pre-mRNA splicing is important to explain proteomic diversity and the misregulation of splicing has been implicated in many disea...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
The Royal Society
2018
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| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915717/ https://www.ncbi.nlm.nih.gov/pubmed/29685977 http://dx.doi.org/10.1098/rstb.2017.0073 |