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Clinically Relevant Plasmid-Host Interactions Indicate that Transcriptional and Not Genomic Modifications Ameliorate Fitness Costs of Klebsiella pneumoniae Carbapenemase-Carrying Plasmids

The rapid dissemination of antimicrobial resistance (AMR) around the globe is largely due to mobile genetic elements, such as plasmids. They confer resistance to critically important drugs, including extended-spectrum beta-lactams, carbapenems, and colistin. Large, complex resistance plasmids have e...

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Detalles Bibliográficos
Autores principales:	Buckner, Michelle M. C., Saw, Howard T. H., Osagie, Rachael N., McNally, Alan, Ricci, Vito, Wand, Matthew E., Woodford, Neil, Ivens, Alasdair, Webber, Mark A., Piddock, Laura J. V.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Society for Microbiology 2018
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915730/ https://www.ncbi.nlm.nih.gov/pubmed/29691332 http://dx.doi.org/10.1128/mBio.02303-17

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