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Human Cytomegalovirus Encodes a Novel FLT3 Receptor Ligand Necessary for Hematopoietic Cell Differentiation and Viral Reactivation

The ability of human cytomegalovirus (HCMV) to reactivate from latent infection of hematopoietic progenitor cells (HPCs) is intimately linked to cellular differentiation. HCMV encodes UL7 that our group has shown is secreted from infected cells and induces angiogenesis. In this study, we show that U...

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Detalles Bibliográficos
Autores principales: Crawford, Lindsey B., Kim, Jung Heon, Collins-McMillen, Donna, Lee, Byeong-Jae, Landais, Igor, Held, Christine, Nelson, Jay A., Yurochko, Andrew D., Caposio, Patrizia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Microbiology 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915732/
https://www.ncbi.nlm.nih.gov/pubmed/29691342
http://dx.doi.org/10.1128/mBio.00682-18