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Promiscuous, Multi-Target Lupane-Type Triterpenoids Inhibits Wild Type and Drug Resistant HIV-1 Replication Through the Interference With Several Targets

Current research on antiretroviral therapy is mainly focused in the development of new formulations or combinations of drugs belonging to already known targets. However, HIV-1 infection is not cured by current therapy and thus, new approaches are needed. Bevirimat was developed by chemical modificat...

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Detalles Bibliográficos
Autores principales: Bedoya, Luis M., Beltrán, Manuela, García-Pérez, Javier, Obregón-Calderón, Patricia, Callies, Oliver, Jímenez, Ignacio A., Bazzocchi, Isabel L., Alcamí, José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915803/
https://www.ncbi.nlm.nih.gov/pubmed/29720939
http://dx.doi.org/10.3389/fphar.2018.00358