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The endoscopic modified lothrop procedure: Review of single institution experience and long‐term outcomes

BACKGROUND: Endoscopic Modified Lothrop Procedure (EMLP) has become a fundamental practice in rhinology. Improvements in symptom burden, ostial patency, morbidity, and costs have surpassed that of an open approach to the frontal sinus. Long‐term efficacy has not been well established. OBJECTIVE: Thi...

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Autores principales: Shen, Jasper, Chan, Nadia, Wrobel, Bozena B.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915830/
https://www.ncbi.nlm.nih.gov/pubmed/29721542
http://dx.doi.org/10.1002/lio2.145
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author Shen, Jasper
Chan, Nadia
Wrobel, Bozena B.
author_facet Shen, Jasper
Chan, Nadia
Wrobel, Bozena B.
author_sort Shen, Jasper
collection PubMed
description BACKGROUND: Endoscopic Modified Lothrop Procedure (EMLP) has become a fundamental practice in rhinology. Improvements in symptom burden, ostial patency, morbidity, and costs have surpassed that of an open approach to the frontal sinus. Long‐term efficacy has not been well established. OBJECTIVE: This study details the long‐term outcomes of EMLP and risk factors for subsequent surgical revision at a single institution. METHODS: This study utilized a retrospective review of patients who underwent EMLP from September 2006 to February 2017 by a single surgeon at an academic tertiary referral center. Patient demographics, indications, symptom burden, and endoscopic assessment of frontal ostium patency were analyzed for their effect on surgical outcome. Risk factors for failures were identified. RESULTS: Seventy‐six consecutive patients with an average age of 58.1 years met the inclusion and exclusion criteria and underwent EMLP for chronic rhinosinusitis (CRS, 59%), neoplasm (26%), and mucoceles (15%). The average number of standard endoscopic sinus surgeries prior to EMLP was 2.9. The mean follow‐up of the cohort was 34.8 months, at the end of which, EMLP was successful in 78% of all patients, requiring no further surgery. Ninety percent of patients reported significant clinical improvement at the most recent follow‐up. Subgroup analysis of CRS patients revealed an equally high success rate but a higher likelihood of ostial closure. Recurrent disease necessitated revision endoscopic surgery in 17 patients, the majority of whom suffered CRS. Only tissue eosinophilia was identified to significantly increase the risk of revision surgery. CONCLUSIONS: The majority of the patients who undergo EMLP achieve sustained patency of the frontal sinus outflow tract and adequate symptom improvement. Prominent tissue eosinophilia identifies patients at risk of requiring additional frontal sinus surgery. LEVEL OF EVIDENCE: 4.
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spelling pubmed-59158302018-05-02 The endoscopic modified lothrop procedure: Review of single institution experience and long‐term outcomes Shen, Jasper Chan, Nadia Wrobel, Bozena B. Laryngoscope Investig Otolaryngol Allergy, Rhinology, and Immunology BACKGROUND: Endoscopic Modified Lothrop Procedure (EMLP) has become a fundamental practice in rhinology. Improvements in symptom burden, ostial patency, morbidity, and costs have surpassed that of an open approach to the frontal sinus. Long‐term efficacy has not been well established. OBJECTIVE: This study details the long‐term outcomes of EMLP and risk factors for subsequent surgical revision at a single institution. METHODS: This study utilized a retrospective review of patients who underwent EMLP from September 2006 to February 2017 by a single surgeon at an academic tertiary referral center. Patient demographics, indications, symptom burden, and endoscopic assessment of frontal ostium patency were analyzed for their effect on surgical outcome. Risk factors for failures were identified. RESULTS: Seventy‐six consecutive patients with an average age of 58.1 years met the inclusion and exclusion criteria and underwent EMLP for chronic rhinosinusitis (CRS, 59%), neoplasm (26%), and mucoceles (15%). The average number of standard endoscopic sinus surgeries prior to EMLP was 2.9. The mean follow‐up of the cohort was 34.8 months, at the end of which, EMLP was successful in 78% of all patients, requiring no further surgery. Ninety percent of patients reported significant clinical improvement at the most recent follow‐up. Subgroup analysis of CRS patients revealed an equally high success rate but a higher likelihood of ostial closure. Recurrent disease necessitated revision endoscopic surgery in 17 patients, the majority of whom suffered CRS. Only tissue eosinophilia was identified to significantly increase the risk of revision surgery. CONCLUSIONS: The majority of the patients who undergo EMLP achieve sustained patency of the frontal sinus outflow tract and adequate symptom improvement. Prominent tissue eosinophilia identifies patients at risk of requiring additional frontal sinus surgery. LEVEL OF EVIDENCE: 4. John Wiley and Sons Inc. 2018-03-23 /pmc/articles/PMC5915830/ /pubmed/29721542 http://dx.doi.org/10.1002/lio2.145 Text en © 2018 The Authors Laryngoscope Investigative Otolaryngology published by Wiley Periodicals, Inc. on behalf of The Triological Society This is an open access article under the terms of the http://creativecommons.org/licenses/by-nc-nd/4.0/ License, which permits use and distribution in any medium, provided the original work is properly cited, the use is non‐commercial and no modifications or adaptations are made.
spellingShingle Allergy, Rhinology, and Immunology
Shen, Jasper
Chan, Nadia
Wrobel, Bozena B.
The endoscopic modified lothrop procedure: Review of single institution experience and long‐term outcomes
title The endoscopic modified lothrop procedure: Review of single institution experience and long‐term outcomes
title_full The endoscopic modified lothrop procedure: Review of single institution experience and long‐term outcomes
title_fullStr The endoscopic modified lothrop procedure: Review of single institution experience and long‐term outcomes
title_full_unstemmed The endoscopic modified lothrop procedure: Review of single institution experience and long‐term outcomes
title_short The endoscopic modified lothrop procedure: Review of single institution experience and long‐term outcomes
title_sort endoscopic modified lothrop procedure: review of single institution experience and long‐term outcomes
topic Allergy, Rhinology, and Immunology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915830/
https://www.ncbi.nlm.nih.gov/pubmed/29721542
http://dx.doi.org/10.1002/lio2.145
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