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MicroRNA-200a/200b Modulate High Glucose-Induced Endothelial Inflammation by Targeting O-linked N-Acetylglucosamine Transferase Expression

Background and Aims: Increased O-linked N-acetylglucosamine (O-GlcNAc) modification of proteins by O-GlcNAc transferase (OGT) is associated with diabetic complications. Furthermore, oxidative stress promotes endothelial inflammation during diabetes. A previous study reported that microRNA-200 (miR-2...

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Detalles Bibliográficos
Autores principales: Lo, Wan-Yu, Yang, Wen-Kai, Peng, Ching-Tien, Pai, Wan-Yu, Wang, Huang-Joe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5915961/
https://www.ncbi.nlm.nih.gov/pubmed/29720943
http://dx.doi.org/10.3389/fphys.2018.00355

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