Cargando…

Neuropsychiatric Phenotypes Produced by GABA Reduction in Mouse Cortex and Hippocampus

Whereas cortical GAD67 reduction and subsequent GABA level decrease are consistently observed in schizophrenia and depression, it remains unclear how these GABAergic abnormalities contribute to specific symptoms. We modeled cortical GAD67 reduction in mice, in which the Gad1 gene is genetically abla...

Descripción completa

Detalles Bibliográficos
Autores principales:	Kolata, Stefan M, Nakao, Kazuhito, Jeevakumar, Vivek, Farmer-Alroth, Emily L, Fujita, Yuko, Bartley, Aundrea F, Jiang, Sunny Zhihong, Rompala, Gregory R, Sorge, Robert E, Jimenez, Dennisse V, Martinowich, Keri, Mateo, Yolanda, Hashimoto, Kenji, Dobrunz, Lynn E, Nakazawa, Kazu
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group 2018
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916365/ https://www.ncbi.nlm.nih.gov/pubmed/29362511 http://dx.doi.org/10.1038/npp.2017.296

Ejemplares similares

Spatial and temporal boundaries of NMDA receptor hypofunction leading to schizophrenia
por: Nakazawa, Kazu, et al.
Publicado: (2017)

Contribution of NMDA Receptor Hypofunction in Prefrontal and Cortical Excitatory Neurons to Schizophrenia-Like Phenotypes
por: Rompala, Gregory R., et al.
Publicado: (2013)

Schizophrenia-Like Dopamine Release Abnormalities in a Mouse Model of NMDA Receptor Hypofunction
por: Nakao, Kazuhito, et al.
Publicado: (2019)

Brain state-dependent abnormal LFP activity in the auditory cortex of a schizophrenia mouse model
por: Nakao, Kazuhito, et al.
Publicado: (2014)

Activity-dependent brain-derived neurotrophic factor expression regulates cortistatin-interneurons and sleep behavior
por: Martinowich, Keri, et al.
Publicado: (2011)

Prefrontal cortex-dependent innate behaviors are altered by selective knockdown of Gad1 in neuropeptide Y interneurons
por: Corder, Katelynn M., et al.
Publicado: (2018)

Molecular evidence for BDNF- and GABA-related dysfunctions in the amygdala of female subjects with Major Depression
por: Guilloux, Jean-Philippe, et al.
Publicado: (2011)

5-HT2A receptor dysregulation in a schizophrenia relevant mouse model of NMDA receptor hypofunction
por: Nakao, Kazuhito, et al.
Publicado: (2022)

Stress in Regulation of GABA Amygdala System and Relevance to Neuropsychiatric Diseases
por: Jie, Fan, et al.
Publicado: (2018)

TWEAKing the Hippocampus: The Effects of TWEAK on the Genomic Fabric of the Hippocampus in a Neuropsychiatric Lupus Mouse Model
por: Iacobas, Dumitru A., et al.
Publicado: (2021)

LSO:Ce Inorganic Scintillators Are Biocompatible With Neuronal and Circuit Function
por: Bartley, Aundrea F., et al.
Publicado: (2019)

Excitatory actions of GABA in the intact neonatal rodent hippocampus in vitro
por: Valeeva, Guzel, et al.
Publicado: (2013)

GABA(A) Receptors Are Well Preserved in the Hippocampus of Aged Mice
por: Palpagama, Thulani H., et al.
Publicado: (2019)

BDNF at the Synapse: Why Location Matters
por: Song, Minseok, et al.
Publicado: (2017)

Convergence of genetic and environmental factors on parvalbumin-positive interneurons in schizophrenia
por: Jiang, Zhihong, et al.
Publicado: (2013)

Glutamate and GABA imbalance promotes neuronal apoptosis in hippocampus after stress
por: Gao, Jie, et al.
Publicado: (2014)

Comparative density of CCK- and PV-GABA cells within the cortex and hippocampus
por: Whissell, Paul D., et al.
Publicado: (2015)

GABA, but Not Bestrophin-1, Is Localized in Astroglial Processes in the Mouse Hippocampus and the Cerebellum
por: Ormel, Lasse, et al.
Publicado: (2020)

GSK3β inhibition restores cortical gamma oscillation and cognitive behavior in a mouse model of NMDA receptor hypofunction relevant to schizophrenia
por: Nakao, Kazuhito, et al.
Publicado: (2020)

A functional role for both γ-aminobutyric acid (GABA) transporter-1 and GABA transporter-3 in the modulation of extracellular GABA and GABAergic tonic conductances in the rat hippocampus
por: Kersanté, Flavie, et al.
Publicado: (2013)

Control of GABA Release at Mossy Fiber-CA3 Connections in the Developing Hippocampus
por: Safiulina, Victoria F., et al.
Publicado: (2010)

Immunohistochemical colocalization of estrogen receptor-α and GABA in adult female rat hippocampus
por: Rai, Anju Lata, et al.
Publicado: (2012)

GABA(A) receptor subunit deregulation in the hippocampus of human foetuses with Down syndrome
por: Milenkovic, Ivan, et al.
Publicado: (2017)

A high-fat diet decreases GABA concentration in the frontal cortex and hippocampus of rats
por: Sandoval-Salazar, Cuauhtemoc, et al.
Publicado: (2016)

Expression of GABA receptor subunits in the hippocampus and thalamus after experimental traumatic brain injury
por: Drexel, Meinrad, et al.
Publicado: (2015)

Astrocytic proBDNF and Tonic GABA Distinguish Active versus Reactive Astrocytes in Hippocampus
por: Chun, Heejung, et al.
Publicado: (2018)

Dysbindin Deficiency Modifies the Expression of GABA Neuron and Ion Permeation Transcripts in the Developing Hippocampus
por: Larimore, Jennifer, et al.
Publicado: (2017)

The effect of age and sex on the expression of GABA signaling components in the human hippocampus and entorhinal cortex
por: Ethiraj, Jayarjun, et al.
Publicado: (2021)

Epipregnanolone as a Positive Modulator of GABA(A) Receptor in Rat Cerebellar and Hippocampus Neurons
por: Bukanova, Julia, et al.
Publicado: (2021)

Neuropsychopharmacology (NPP) 2020 report on gender balance among corresponding authors and reviewers: before and during the COVID-19 pandemic
por: Hupalo, Sofiya, et al.
Publicado: (2022)

Protein kinase C regulates tonic GABA(A) receptor-mediated inhibition in the hippocampus and thalamus
por: Bright, Damian P, et al.
Publicado: (2013)

GABA (A ) Receptors in the Dorsal Hippocampus are Involved in Sate-dependent Learning Induced by Lithium in Mice
por: Parsaei, Leila, et al.
Publicado: (2011)

Synaptic pruning in the female hippocampus is triggered at puberty by extrasynaptic GABA(A) receptors on dendritic spines
por: Afroz, Sonia, et al.
Publicado: (2016)

Impact of Developmental Changes of GABA(A) Receptors on Interneuron-NG2 Glia Transmission in the Hippocampus
por: Patt, Linda, et al.
Publicado: (2023)

Balanced gene regulation by an embryonic brain non-coding RNA is critical for GABA circuitry in adult hippocampus
por: Bond, Allison M., et al.
Publicado: (2009)

Acutely increasing δGABA(A) receptor activity impairs memory and inhibits synaptic plasticity in the hippocampus
por: Whissell, Paul D., et al.
Publicado: (2013)

Density of GABA(B) Receptors Is Reduced in Granule Cells of the Hippocampus in a Mouse Model of Alzheimer’s Disease
por: Martín-Belmonte, Alejandro, et al.
Publicado: (2020)

Lamotrigine Attenuates Neuronal Excitability, Depresses GABA Synaptic Inhibition, and Modulates Theta Rhythms in Rat Hippocampus
por: Kazmierska-Grebowska, Paulina, et al.
Publicado: (2021)

Nanoscale alterations in GABA(B) receptors and GIRK channel organization on the hippocampus of APP/PS1 mice
por: Martín-Belmonte, Alejandro, et al.
Publicado: (2022)

BACE1 Regulates Proliferation and Neuronal Differentiation of Newborn Cells in the Adult Hippocampus in Mice
por: Chatila, Zena K., et al.
Publicado: (2018)

Cannot write session to /tmp/vufind_sessions/sess_usfd0p3iookihs6rtb6ikcr13p