Smart polymeric nanoparticles with pH-responsive and PEG-detachable properties for co-delivering paclitaxel and survivin siRNA to enhance antitumor outcomes

BACKGROUND: The co-delivery of chemotherapeutic agents and small interfering RNA (siRNA) within one cargo can enhance the anticancer outcomes through its synergistic therapeutic effects. MATERIALS AND METHODS: We prepared smart polymeric nanoparticles (NPs) with pH-responsive and poly(ethylene glyco...

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Detalles Bibliográficos
Autores principales: Jin, Mingji, Jin, Guangming, Kang, Lin, Chen, Liqing, Gao, Zhonggao, Huang, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Dove Medical Press 2018
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916383/
https://www.ncbi.nlm.nih.gov/pubmed/29719390
http://dx.doi.org/10.2147/IJN.S161426

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916383/
https://www.ncbi.nlm.nih.gov/pubmed/29719390
http://dx.doi.org/10.2147/IJN.S161426

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