Efficient Multicomponent Active Template Synthesis of Catenanes

[Image: see text] We describe a simple and high yielding active template synthesis of [2]catenanes. In addition to mechanical bond formation using a single premacrocycle bearing an azide and alkyne moiety, our method is also suitable for the co-macrocyclization of readily available bis-alkyne and bi...

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Autores principales: Lewis, James E. M., Modicom, Florian, Goldup, Stephen M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2018
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916464/
https://www.ncbi.nlm.nih.gov/pubmed/29558129
http://dx.doi.org/10.1021/jacs.8b01602
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author Lewis, James E. M.
Modicom, Florian
Goldup, Stephen M.
author_facet Lewis, James E. M.
Modicom, Florian
Goldup, Stephen M.
author_sort Lewis, James E. M.
collection PubMed
description [Image: see text] We describe a simple and high yielding active template synthesis of [2]catenanes. In addition to mechanical bond formation using a single premacrocycle bearing an azide and alkyne moiety, our method is also suitable for the co-macrocyclization of readily available bis-alkyne and bis-azide comonomers and even short alkyne/azide components which oligomerize prior to mechanical bond formation.
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spelling pubmed-59164642018-04-27 Efficient Multicomponent Active Template Synthesis of Catenanes Lewis, James E. M. Modicom, Florian Goldup, Stephen M. J Am Chem Soc [Image: see text] We describe a simple and high yielding active template synthesis of [2]catenanes. In addition to mechanical bond formation using a single premacrocycle bearing an azide and alkyne moiety, our method is also suitable for the co-macrocyclization of readily available bis-alkyne and bis-azide comonomers and even short alkyne/azide components which oligomerize prior to mechanical bond formation. American Chemical Society 2018-03-20 2018-04-11 /pmc/articles/PMC5916464/ /pubmed/29558129 http://dx.doi.org/10.1021/jacs.8b01602 Text en Copyright © 2018 American Chemical Society This is an open access article published under a Creative Commons Attribution (CC-BY) License (http://pubs.acs.org/page/policy/authorchoice_ccby_termsofuse.html) , which permits unrestricted use, distribution and reproduction in any medium, provided the author and source are cited.
spellingShingle Lewis, James E. M.
Modicom, Florian
Goldup, Stephen M.
Efficient Multicomponent Active Template Synthesis of Catenanes
title Efficient Multicomponent Active Template Synthesis of Catenanes
title_full Efficient Multicomponent Active Template Synthesis of Catenanes
title_fullStr Efficient Multicomponent Active Template Synthesis of Catenanes
title_full_unstemmed Efficient Multicomponent Active Template Synthesis of Catenanes
title_short Efficient Multicomponent Active Template Synthesis of Catenanes
title_sort efficient multicomponent active template synthesis of catenanes
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916464/
https://www.ncbi.nlm.nih.gov/pubmed/29558129
http://dx.doi.org/10.1021/jacs.8b01602
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