FTI-277 inhibits smooth muscle cell calcification by up-regulating PI3K/Akt signaling and inhibiting apoptosis

BACKGROUND: Vascular calcification is associated with increased cardiovascular morbidity and mortality in patients with atherosclerosis, diabetes and chronic kidney disease. However, no viable treatments for this condition have been identified. This study aimed to determine whether farnesyl transfer...

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Detalles Bibliográficos
Autores principales: Ponnusamy, Arvind, Sinha, Smeeta, Hyde, Gareth D., Borland, Samantha J., Taylor, Rebecca F., Pond, Emma, Eyre, Heather J., Inkson, Colette A., Gilmore, Andrew, Ashton, Nick, Kalra, Philip A., Canfield, Ann E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2018
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916518/
https://www.ncbi.nlm.nih.gov/pubmed/29689070
http://dx.doi.org/10.1371/journal.pone.0196232

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916518/
https://www.ncbi.nlm.nih.gov/pubmed/29689070
http://dx.doi.org/10.1371/journal.pone.0196232

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