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Rapid progress towards elimination of lymphatic filariasis in endemic regions of Myanmar as a result of 16 years of anti-filarial activities (2001–2016)

BACKGROUND: As Myanmar progresses towards lymphatic filariasis (LF) elimination, it is important to know how well the anti-filarial activities have performed. The present study was conducted to study the implementation of the key anti-filarial activities and their impact on key indicators of LF tran...

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Autores principales: Win, Kyawt Mon, Tripathy, Jaya Prasad, Maung, Thae Maung, Oo, Tin, Thi, Aung, Lon, Khin Nan, Lin, Zaw
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916724/
https://www.ncbi.nlm.nih.gov/pubmed/29720887
http://dx.doi.org/10.1186/s41182-018-0093-x
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author Win, Kyawt Mon
Tripathy, Jaya Prasad
Maung, Thae Maung
Oo, Tin
Thi, Aung
Lon, Khin Nan
Lin, Zaw
author_facet Win, Kyawt Mon
Tripathy, Jaya Prasad
Maung, Thae Maung
Oo, Tin
Thi, Aung
Lon, Khin Nan
Lin, Zaw
author_sort Win, Kyawt Mon
collection PubMed
description BACKGROUND: As Myanmar progresses towards lymphatic filariasis (LF) elimination, it is important to know how well the anti-filarial activities have performed. The present study was conducted to study the implementation of the key anti-filarial activities and their impact on key indicators of LF transmission. METHODS: A secondary analysis of aggregate program data on the anti-filarial activities was conducted in four endemic state/regions of Myanmar receiving at least six mass drug administration (MDA) rounds during 2001–2016. RESULTS: MDA coverage has been expanded to cover all the endemic implementation units (IUs), i.e., 45 by 2015 and 6 IUs out of them have already stopped MDA. The reported coverage of MDA ranges from 87 to 100% whereas surveyed coverage ranges from 78 to 100% among the eligible population. The prevalence of microfilaria has significantly declined especially in Magway from 4.7 to 0.2% and Sagaing region from 7.9 to 1.3% during 2001–2016. Around 2.5% of estimated cases of hydrocele were reported to the program during 2009–2014. CONCLUSION: Myanmar has achieved significant success in interrupting LF transmission through several MDA rounds with high coverage. However, morbidity reporting and management, being in its initial phase requires an active surveillance system for identifying and managing people with LF-associated morbidities under the program.
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spelling pubmed-59167242018-05-02 Rapid progress towards elimination of lymphatic filariasis in endemic regions of Myanmar as a result of 16 years of anti-filarial activities (2001–2016) Win, Kyawt Mon Tripathy, Jaya Prasad Maung, Thae Maung Oo, Tin Thi, Aung Lon, Khin Nan Lin, Zaw Trop Med Health Research BACKGROUND: As Myanmar progresses towards lymphatic filariasis (LF) elimination, it is important to know how well the anti-filarial activities have performed. The present study was conducted to study the implementation of the key anti-filarial activities and their impact on key indicators of LF transmission. METHODS: A secondary analysis of aggregate program data on the anti-filarial activities was conducted in four endemic state/regions of Myanmar receiving at least six mass drug administration (MDA) rounds during 2001–2016. RESULTS: MDA coverage has been expanded to cover all the endemic implementation units (IUs), i.e., 45 by 2015 and 6 IUs out of them have already stopped MDA. The reported coverage of MDA ranges from 87 to 100% whereas surveyed coverage ranges from 78 to 100% among the eligible population. The prevalence of microfilaria has significantly declined especially in Magway from 4.7 to 0.2% and Sagaing region from 7.9 to 1.3% during 2001–2016. Around 2.5% of estimated cases of hydrocele were reported to the program during 2009–2014. CONCLUSION: Myanmar has achieved significant success in interrupting LF transmission through several MDA rounds with high coverage. However, morbidity reporting and management, being in its initial phase requires an active surveillance system for identifying and managing people with LF-associated morbidities under the program. BioMed Central 2018-04-16 /pmc/articles/PMC5916724/ /pubmed/29720887 http://dx.doi.org/10.1186/s41182-018-0093-x Text en © The Author(s) 2018 Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.
spellingShingle Research
Win, Kyawt Mon
Tripathy, Jaya Prasad
Maung, Thae Maung
Oo, Tin
Thi, Aung
Lon, Khin Nan
Lin, Zaw
Rapid progress towards elimination of lymphatic filariasis in endemic regions of Myanmar as a result of 16 years of anti-filarial activities (2001–2016)
title Rapid progress towards elimination of lymphatic filariasis in endemic regions of Myanmar as a result of 16 years of anti-filarial activities (2001–2016)
title_full Rapid progress towards elimination of lymphatic filariasis in endemic regions of Myanmar as a result of 16 years of anti-filarial activities (2001–2016)
title_fullStr Rapid progress towards elimination of lymphatic filariasis in endemic regions of Myanmar as a result of 16 years of anti-filarial activities (2001–2016)
title_full_unstemmed Rapid progress towards elimination of lymphatic filariasis in endemic regions of Myanmar as a result of 16 years of anti-filarial activities (2001–2016)
title_short Rapid progress towards elimination of lymphatic filariasis in endemic regions of Myanmar as a result of 16 years of anti-filarial activities (2001–2016)
title_sort rapid progress towards elimination of lymphatic filariasis in endemic regions of myanmar as a result of 16 years of anti-filarial activities (2001–2016)
topic Research
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916724/
https://www.ncbi.nlm.nih.gov/pubmed/29720887
http://dx.doi.org/10.1186/s41182-018-0093-x
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