Cargando…

Cardiomyocyte Lineage Specification in Adult Human Cardiac Precursor Cells Via Modulation of Enhancer-Associated Long Noncoding RNA Expression

The mechanisms controlling differentiation in adult cardiac precursor cells (CPCs) are still largely unknown. In this study, CPCs isolated from the human heart were found to produce predominantly smooth muscle cells but could be redirected to the cardiomyocyte fate by transient activation followed b...

Descripción completa

Detalles Bibliográficos
Autores principales:	Plaisance, Isabelle, Perruchoud, Stéphanie, Fernandez-Tenorio, Miguel, Gonzales, Christine, Ounzain, Samir, Ruchat, Patrick, Nemir, Mohamed, Niggli, Ernst, Pedrazzini, Thierry
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Elsevier 2016
Materias:	PRECLINICAL RESEARCH
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916868/ https://www.ncbi.nlm.nih.gov/pubmed/29707678 http://dx.doi.org/10.1016/j.jacbts.2016.06.008

Ejemplares similares

A transposable element into the human long noncoding RNA CARMEN is a switch for cardiac precursor cell specification
por: Plaisance, Isabelle, et al.
Publicado: (2022)

Inhibition of the NOTCH1 Pathway in the Stressed Heart Limits Fibrosis and Promotes Recruitment of Non-Myocyte Cells into the Cardiomyocyte Fate
por: Nemir, Mohamed, et al.
Publicado: (2022)

Functional importance of cardiac enhancer-associated noncoding RNAs in heart development and disease
por: Ounzain, Samir, et al.
Publicado: (2014)

The Notch pathway controls fibrotic and regenerative repair in the adult heart
por: Nemir, Mohamed, et al.
Publicado: (2014)

FIMICS: A panel of long noncoding RNAs for cardiovascular conditions()
por: Firat, Huseyin, et al.
Publicado: (2023)

Comparative transcriptome profiling of the injured zebrafish and mouse hearts identifies miRNA-dependent repair pathways
por: Crippa, Stefania, et al.
Publicado: (2016)

Carvedilol Prevents Redox Inactivation of Cardiomyocyte Β(1)-Adrenergic Receptors
por: Park, Misun, et al.
Publicado: (2018)

Cardiac Microvascular Endothelial Enhancement of Cardiomyocyte Function Is Impaired by Inflammation and Restored by Empagliflozin
por: Juni, Rio P., et al.
Publicado: (2019)

Discovery of a Small Molecule to Increase Cardiomyocytes and Protect the Heart After Ischemic Injury
por: Hara, Hironori, et al.
Publicado: (2018)

Extracellular Matrix From Hypertrophic Myocardium Provokes Impaired Twitch Dynamics in Healthy Cardiomyocytes
por: Sewanan, Lorenzo R., et al.
Publicado: (2019)

Macrophage-Derived Exosomal Mir-155 Regulating Cardiomyocyte Pyroptosis and Hypertrophy in Uremic Cardiomyopathy
por: Wang, Bin, et al.
Publicado: (2020)

A transcribed enhancer dictates mesendoderm specification in pluripotency
por: Alexanian, Michael, et al.
Publicado: (2017)

Cardiomyocyte SMAD4-Dependent TGF-β Signaling is Essential to Maintain Adult Heart Homeostasis
por: Umbarkar, Prachi, et al.
Publicado: (2019)

Role of Blood Oxygen Saturation During Post-Natal Human Cardiomyocyte Cell Cycle Activities
por: Ye, Lincai, et al.
Publicado: (2020)

FYCO1 Regulates Cardiomyocyte Autophagy and Prevents Heart Failure Due to Pressure Overload In Vivo
por: Kuhn, Christian, et al.
Publicado: (2021)

Gene Therapy Rescues Cardiac Dysfunction in Duchenne Muscular Dystrophy Mice by Elevating Cardiomyocyte Deoxy-Adenosine Triphosphate
por: Kolwicz, Stephen C., et al.
Publicado: (2019)

Abstract 23 HLA-Homozygous iPSC from Cord Blood for the Generation of Cardiomyocytes for Allogeneic Cell Therapy to the Heart
por: Becker, Fabienne, et al.
Publicado: (2023)

Genome-wide profiling of the cardiac transcriptome after myocardial infarction identifies novel heart-specific long non-coding RNAs
por: Ounzain, Samir, et al.
Publicado: (2015)

PDGF-AB Reduces Myofibroblast Differentiation Without Increasing Proliferation After Myocardial Infarction
por: Hume, Robert D., et al.
Publicado: (2023)

Noncoding RNA and Cardiomyocyte Proliferation
por: Qu, Shuang, et al.
Publicado: (2017)

Jagged1 intracellular domain-mediated inhibition of Notch1 signalling regulates cardiac homeostasis in the postnatal heart
por: Metrich, Mélanie, et al.
Publicado: (2015)

IFN-γ-STAT1-ERK Pathway Mediates Protective Effects of Invariant Natural Killer T Cells Against Doxorubicin-Induced Cardiomyocyte Death
por: Sada, Masashi, et al.
Publicado: (2023)

zDHHC9 Regulates Cardiomyocyte Rab3a Activity and Atrial Natriuretic Peptide Secretion Through Palmitoylation of Rab3gap1
por: Essandoh, Kobina, et al.
Publicado: (2023)

Effects of salinomycin and niclosamide on small cell lung cancer and small cell lung cancer circulating tumor cell lines
por: Hochmair, Maximilian, et al.
Publicado: (2019)

Efficacy of fluvastatin and aspirin for prevention of hormonally insensitive breast cancer
por: Bhardwaj, Anjana, et al.
Publicado: (2021)

Return of the Tbx5; lineage-tracing reveals ventricular cardiomyocyte-like precursors in the injured adult mammalian heart
por: Siatra, Panagiota, et al.
Publicado: (2023)

Transcatheter Tricuspid Valve Implantation of NaviGate Bioprosthesis in a Preclinical Model
por: Navia, Jose L., et al.
Publicado: (2018)

ALDH1A3 Is the Key Isoform That Contributes to Aldehyde Dehydrogenase Activity and Affects in Vitro Proliferation in Cardiac Atrial Appendage Progenitor Cells
por: Puttini, Stefania, et al.
Publicado: (2018)

Circulating tumor cells in non-metastatic triple-negative breast cancer
por: Karhade, Mandar, et al.
Publicado: (2014)

Trastuzumab uptake and its relation to efficacy in an animal model of HER2-positive breast cancer brain metastasis
por: Lewis Phillips, Gail D., et al.
Publicado: (2017)

Estrogen receptor splice variants as a potential source of false-positive estrogen receptor status in breast cancer diagnostics
por: Groenendijk, Floris H., et al.
Publicado: (2013)

Identification, Selection, and Enrichment of Cardiomyocyte Precursors
por: Zanetti, Bianca Ferrarini, et al.
Publicado: (2013)

Chemotherapy in vivo against M109 murine lung carcinoma with cytochalasin B by localized, systemic, and liposomal administration
por: Trendowski, Matthew, et al.
Publicado: (2015)

Chemotherapy with cytochalasin congeners in vitro and in vivo against murine models
por: Trendowski, Matthew, et al.
Publicado: (2015)

Reduced menin expression leads to decreased ERα expression and is correlated with the occurrence of human luminal B-like and ER-negative breast cancer subtypes
por: Teinturier, Romain, et al.
Publicado: (2021)

Control of the adaptive response of the heart to stress via the Notch1 receptor pathway
por: Croquelois, Adrien, et al.
Publicado: (2008)

Long-term blinded placebo-controlled study of SNT-MC17/idebenone in the dystrophin deficient mdx mouse: cardiac protection and improved exercise performance
por: Buyse, Gunnar M., et al.
Publicado: (2009)

Comparison of microfluidic platforms for the enrichment of circulating tumor cells in breast cancer patients
por: Sajdik, Constantin, et al.
Publicado: (2022)

A prospective study to assess the clinical utility of serum HER2 extracellular domain in breast cancer with HER2 overexpression
por: Reix, Nathalie, et al.
Publicado: (2016)

A83-01 inhibits TGF-β-induced upregulation of Wnt3 and epithelial to mesenchymal transition in HER2-overexpressing breast cancer cells
por: Wu, Yanyuan, et al.
Publicado: (2017)

Cannot write session to /tmp/vufind_sessions/sess_dsgrggalqv95vl51mvoogcqii0