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Non-canonical activation of hedgehog in prostate cancer cells mediated by the interaction of transcriptionally active androgen receptor proteins with Gli3

Hedgehog (Hh) is an oncogenic signaling pathway that regulates the activity of Gli transcription factors. Canonical Hh is a Smoothened- (Smo-) driven process that alters the post-translational processing of Gli2/Gli3 proteins. Though evidence supports a role for Gli action in prostate cancer (PCa) c...

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Detalles Bibliográficos
Autores principales:	Li, Na, Truong, Sarah, Nouri, Mannan, Moore, Jackson, Al Nakouzi, Nader, Lubik, Amy Anne, Buttyan, Ralph
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2018
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916917/ https://www.ncbi.nlm.nih.gov/pubmed/29429990 http://dx.doi.org/10.1038/s41388-017-0098-7

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