Obesity exacerbates colitis-associated cancer via IL-6-regulated macrophage polarisation and CCL-20/CCR-6-mediated lymphocyte recruitment

Colorectal cancer (CRC) is one of the most lethal cancers worldwide in which the vast majority of cases exhibit little genetic risk but are associated with a sedentary lifestyle and obesity. Although the mechanisms underlying CRC and colitis-associated colorectal cancer (CAC) remain unclear, we hypo...

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Detalles Bibliográficos
Autores principales: Wunderlich, Claudia M., Ackermann, P. Justus, Ostermann, Anna Lena, Adams-Quack, Petra, Vogt, Merly C., Tran, My-Ly, Nikolajev, Alexei, Waisman, Ari, Garbers, Christoph, Theurich, Sebastian, Mauer, Jan, Hövelmeyer, Nadine, Wunderlich, F. Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2018
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916940/
https://www.ncbi.nlm.nih.gov/pubmed/29695802
http://dx.doi.org/10.1038/s41467-018-03773-0

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