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Tribody [(HER2)(2)xCD16] Is More Effective Than Trastuzumab in Enhancing γδ T Cell and Natural Killer Cell Cytotoxicity Against HER2-Expressing Cancer Cells
An enhanced expression of human epidermal growth factor receptor 2 (HER2, ErbB2) often occurs in an advanced stage of breast, ovarian, gastric or esophageal cancer, and pancreatic ductal adenocarcinoma (PDAC). Commonly, HER2 expression is associated with poor clinical outcome or chemoresistance in o...
Autores principales: | Oberg, Hans H., Kellner, Christian, Gonnermann, Daniel, Sebens, Susanne, Bauerschlag, Dirk, Gramatzki, Martin, Kabelitz, Dieter, Peipp, Matthias, Wesch, Daniela |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Frontiers Media S.A.
2018
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916959/ https://www.ncbi.nlm.nih.gov/pubmed/29725336 http://dx.doi.org/10.3389/fimmu.2018.00814 |
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