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Tribody [(HER2)(2)xCD16] Is More Effective Than Trastuzumab in Enhancing γδ T Cell and Natural Killer Cell Cytotoxicity Against HER2-Expressing Cancer Cells

An enhanced expression of human epidermal growth factor receptor 2 (HER2, ErbB2) often occurs in an advanced stage of breast, ovarian, gastric or esophageal cancer, and pancreatic ductal adenocarcinoma (PDAC). Commonly, HER2 expression is associated with poor clinical outcome or chemoresistance in o...

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Detalles Bibliográficos
Autores principales: Oberg, Hans H., Kellner, Christian, Gonnermann, Daniel, Sebens, Susanne, Bauerschlag, Dirk, Gramatzki, Martin, Kabelitz, Dieter, Peipp, Matthias, Wesch, Daniela
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5916959/
https://www.ncbi.nlm.nih.gov/pubmed/29725336
http://dx.doi.org/10.3389/fimmu.2018.00814

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