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Synthesis of N-peptide-6-amino-D-luciferin Conjugates

A general strategy for the synthesis of N-peptide-6-amino-D-luciferin conjugates has been developed. The applicability of the strategy was demonstrated with the preparation of a known substrate, N-Z-Asp-Glu-Val-Asp-6-amino-D-luciferin (N-Z-DEVD-aLuc). N-Z-DEVD-aLuc was obtained via a hybrid liquid/s...

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Detalles Bibliográficos
Autores principales: Kovács, Anita K., Hegyes, Péter, Szebeni, Gábor J., Nagy, Lajos I., Puskás, László G., Tóth, Gábor K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917020/
https://www.ncbi.nlm.nih.gov/pubmed/29725588
http://dx.doi.org/10.3389/fchem.2018.00120