Cargando…

Necrostatin-1 Attenuates Cisplatin-Induced Nephrotoxicity Through Suppression of Apoptosis and Oxidative Stress and Retains Klotho Expression

Aim: Cisplatin is an effective chemotherapeutic drug, but the application in clinical is greatly limited by its nephrotoxicity. Necrostatin-1 (Nec-1), an inhibitor of RIP1 kinase, has been reported to inhibit RIP-mediated necroptosis. The aim of this study is to detect the protective effects of Nec-...

Descripción completa

Detalles Bibliográficos
Autores principales:	Ning, Yichun, Shi, Yiqin, Chen, Jing, Song, Nana, Cai, Jieru, Fang, Yi, Yu, Xiaofang, Ji, Jun, Ding, Xiaoqiang
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917042/ https://www.ncbi.nlm.nih.gov/pubmed/29725301 http://dx.doi.org/10.3389/fphar.2018.00384

Ejemplares similares

Genistein Ameliorates Renal Fibrosis Through Regulation Snail via m6A RNA Demethylase ALKBH5
por: Ning, Yichun, et al.
Publicado: (2020)

Hydrogen-Rich Saline Alleviates Kidney Fibrosis Following AKI and Retains Klotho Expression
por: Chen, Jing, et al.
Publicado: (2017)

Dibenzazepine Attenuates Against Cisplatin-Induced Nephrotoxicity in Rats: Involvement of NOTCH Pathway
por: Abd El-Rhman, Rana H., et al.
Publicado: (2020)

Isoquercitrin Ameliorates Cisplatin-Induced Nephrotoxicity Via the Inhibition of Apoptosis, Inﬂammation, and Oxidative Stress
por: Wang, Hao, et al.
Publicado: (2020)

Receptor of Advanced Glycation End Products Deficiency Attenuates Cisplatin-Induced Acute Nephrotoxicity by Inhibiting Apoptosis, Inflammation and Restoring Fatty Acid Oxidation
por: Wang, Qiang, et al.
Publicado: (2022)

S-Allylmercaptocysteine Attenuates Cisplatin-Induced Nephrotoxicity through Suppression of Apoptosis, Oxidative Stress, and Inflammation
por: Zhu, Xiaosong, et al.
Publicado: (2017)

Isoorientin Attenuates Cisplatin-Induced Nephrotoxicity Through the Inhibition of Oxidative Stress and Apoptosis via Activating the SIRT1/SIRT6/Nrf-2 Pathway
por: Fan, Xiaoye, et al.
Publicado: (2020)

Corrigendum: Receptor of advanced glycation end products deficiency attenuates cisplatin-induced acute nephrotoxicity by inhibiting apoptosis, inflammation and restoring fatty acid oxidation
por: Wang, Qiang, et al.
Publicado: (2022)

Daphnetin Attenuated Cisplatin-Induced Acute Nephrotoxicity With Enhancing Antitumor Activity of Cisplatin by Upregulating SIRT1/SIRT6-Nrf2 Pathway
por: Fan, Xiaoye, et al.
Publicado: (2020)

Genetic Variations and Cisplatin Nephrotoxicity: A Systematic Review
por: Zazuli, Zulfan, et al.
Publicado: (2018)

Necrostatin-1 Attenuates Trauma-Induced Mouse Osteoarthritis and IL-1β Induced Apoptosis via HMGB1/TLR4/SDF-1 in Primary Mouse Chondrocytes
por: Liang, Shuang, et al.
Publicado: (2018)

Antiaging Gene Klotho Attenuates Pancreatic β-Cell Apoptosis in Type 1 Diabetes
por: Lin, Yi, et al.
Publicado: (2015)

High Phosphate Induces and Klotho Attenuates Kidney Epithelial Senescence and Fibrosis
por: Maique, Jenny, et al.
Publicado: (2020)

Leonotis ocymifolia (Burm.f.) Iwarsson aerial parts aqueous extract mitigates cisplatin-induced nephrotoxicity via attenuation of inflammation, and DNA damage
por: Mufti, Afoua, et al.
Publicado: (2023)

Bismuth Reduces Cisplatin-Induced Nephrotoxicity Via Enhancing Glutathione Conjugation and Vesicular Transport
por: Jiang, Hui, et al.
Publicado: (2022)

Persistent Activation of Autophagy After Cisplatin Nephrotoxicity Promotes Renal Fibrosis and Chronic Kidney Disease
por: Fu, Ying, et al.
Publicado: (2022)

Epigallocatechin Gallate Attenuates Gentamicin-Induced Nephrotoxicity by Suppressing Apoptosis and Ferroptosis
por: Yue, Lin, et al.
Publicado: (2022)

Therapeutic Potential and Molecular Mechanisms of Emblica officinalis Gaertn in Countering Nephrotoxicity in Rats Induced by the Chemotherapeutic Agent Cisplatin
por: Malik, Salma, et al.
Publicado: (2016)

Comparison of Myelotoxicity and Nephrotoxicity Between Daily Low-Dose Cisplatin With Concurrent Radiation and Cyclic High-Dose Cisplatin in Non-Small Cell Lung Cancer Patients
por: Zazuli, Zulfan, et al.
Publicado: (2020)

Neferine Attenuates Acute Kidney Injury by Inhibiting NF-κB Signaling and Upregulating Klotho Expression
por: Li, Huihui, et al.
Publicado: (2019)

Necroptosis, necrostatins and tissue injury
por: Smith, Christopher CT, et al.
Publicado: (2011)

Necrostatin-1 enhances the resolution of inflammation by specifically inducing neutrophil apoptosis
por: Jie, Hongyu, et al.
Publicado: (2016)

Protective Effect of Pyxinol, One Active Ingredient of Lichenes on Cisplatin-Induced Nephrotoxicity via Ameliorating DNA Damage Response
por: Yang, Yanting, et al.
Publicado: (2021)

An Optimized Two-Herb Chinese Food as Medicine Formula Reduces Cisplatin-Induced Nephrotoxicity in the Treatment of Lung Cancer in Mice
por: Shi, Le, et al.
Publicado: (2022)

Azadirachta indica Attenuates Cisplatin-Induced Nephrotoxicity and Oxidative Stress
por: Abdel Moneim, Ahmed E., et al.
Publicado: (2014)

Mechanisms of Cisplatin Nephrotoxicity
por: Miller, Ronald P., et al.
Publicado: (2010)

Prevention of cisplatin nephrotoxicity
por: Hayati, Fatemeh, et al.
Publicado: (2015)

Klotho as Potential Autophagy Regulator and Therapeutic Target
por: Zhou, Hongjing, et al.
Publicado: (2021)

Induction of Apoptosis in TNF-Treated L929 Cells in the Presence of Necrostatin-1
por: Sawai, Hirofumi
Publicado: (2016)

Curcumin Ameliorates Cisplatin-Induced Nephrotoxicity and Potentiates Its Anticancer Activity in SD Rats: Potential Role of Curcumin in Breast Cancer Chemotherapy
por: Kumar, Parveen, et al.
Publicado: (2017)

Necrostatin-1 protection of dopaminergic neurons
por: Wu, Jing-ru, et al.
Publicado: (2015)

Hair growth promotion by Necrostatin-1s
por: Zheng, Mei, et al.
Publicado: (2020)

Protocatechuic Aldehyde Attenuates Cisplatin-Induced Acute Kidney Injury by Suppressing Nox-Mediated Oxidative Stress and Renal Inflammation
por: Gao, Li, et al.
Publicado: (2016)

Targeting NEDDylation is a Novel Strategy to Attenuate Cisplatin-induced Nephrotoxicity
por: Jones, Trace M., et al.
Publicado: (2023)

Pioglitazone alleviates cisplatin nephrotoxicity by suppressing mitochondria‐mediated apoptosis via SIRT1/p53 signalling
por: Zhang, Jiong, et al.
Publicado: (2020)

Temporal trends in prevalence and mortality for chronic kidney disease in China from 1990 to 2019: an analysis of the Global Burden of Disease Study 2019
por: Li, Yang, et al.
Publicado: (2022)

Nephrotoxicity of Herbal Medicine and Its Prevention
por: Xu, Xiaofen, et al.
Publicado: (2020)

Galectin 3 inhibition attenuates renal injury progression in cisplatin-induced nephrotoxicity
por: Li, Hong-yan, et al.
Publicado: (2018)

The controversy of klotho as a potential biomarker in chronic kidney disease
por: Yu, Li-Xia, et al.
Publicado: (2022)

Toxicity of Necrostatin-1 in Parkinson’s Disease Models
por: Alegre-Cortés, Eva, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_gfk3m2v8oha0t8rvjpcj65kmeo