Cargando…

Ultrasonographic Evaluation of Parathyroid Hyperplasia in Dialysis Patients

Secondary hyperparathyroidism (SHPT) is one of the most common complications in patients with chronic kidney disease (CKD). Bone and mineral disorders, increased morbidity and mortality are the consequences of SHPT. Therefore, prevention and control of hyperparathyroidism is one of the main objectiv...

Descripción completa

Detalles Bibliográficos
Autores principales: Pavlovic, Drasko, Tomic Brzac, Hrvojka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917120/
https://www.ncbi.nlm.nih.gov/pubmed/17173178
http://dx.doi.org/10.1100/tsw.2006.273
_version_ 1783317133559595008
author Pavlovic, Drasko
Tomic Brzac, Hrvojka
author_facet Pavlovic, Drasko
Tomic Brzac, Hrvojka
author_sort Pavlovic, Drasko
collection PubMed
description Secondary hyperparathyroidism (SHPT) is one of the most common complications in patients with chronic kidney disease (CKD). Bone and mineral disorders, increased morbidity and mortality are the consequences of SHPT. Therefore, prevention and control of hyperparathyroidism is one of the main objectives in the management of patients with CKD, particularly in dialysis patients.It is well known that SHPT in CKD is not only a state of increased parathyroid hormone (PTH) synthesis and secretion, but more importantly, it is a state of parathyroid gland (PTG) hyperplasia. The serum concentration of intact PTH is the main method used to assess PTG overactivity. Unfortunately, estimating the size and shape of the PTG in SHPT diagnosis, i.e., parathyroid hyperplasia, is still neglected. Among the various procedures, ultrasonography could be the method of choice to detect PTG size and shape because of its simplicity and noninvasiveness. This method can be sufficiently sensitive to distinguish diffuse and nodular hyperplasia.
format Online
Article
Text
id pubmed-5917120
institution National Center for Biotechnology Information
language English
publishDate 2006
publisher TheScientificWorldJOURNAL
record_format MEDLINE/PubMed
spelling pubmed-59171202018-06-03 Ultrasonographic Evaluation of Parathyroid Hyperplasia in Dialysis Patients Pavlovic, Drasko Tomic Brzac, Hrvojka ScientificWorldJournal Mini-Review Article Secondary hyperparathyroidism (SHPT) is one of the most common complications in patients with chronic kidney disease (CKD). Bone and mineral disorders, increased morbidity and mortality are the consequences of SHPT. Therefore, prevention and control of hyperparathyroidism is one of the main objectives in the management of patients with CKD, particularly in dialysis patients.It is well known that SHPT in CKD is not only a state of increased parathyroid hormone (PTH) synthesis and secretion, but more importantly, it is a state of parathyroid gland (PTG) hyperplasia. The serum concentration of intact PTH is the main method used to assess PTG overactivity. Unfortunately, estimating the size and shape of the PTG in SHPT diagnosis, i.e., parathyroid hyperplasia, is still neglected. Among the various procedures, ultrasonography could be the method of choice to detect PTG size and shape because of its simplicity and noninvasiveness. This method can be sufficiently sensitive to distinguish diffuse and nodular hyperplasia. TheScientificWorldJOURNAL 2006-12-15 /pmc/articles/PMC5917120/ /pubmed/17173178 http://dx.doi.org/10.1100/tsw.2006.273 Text en Copyright © 2006 Drasko Pavlovic and Hrvojka Tomic Brzac. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Mini-Review Article
Pavlovic, Drasko
Tomic Brzac, Hrvojka
Ultrasonographic Evaluation of Parathyroid Hyperplasia in Dialysis Patients
title Ultrasonographic Evaluation of Parathyroid Hyperplasia in Dialysis Patients
title_full Ultrasonographic Evaluation of Parathyroid Hyperplasia in Dialysis Patients
title_fullStr Ultrasonographic Evaluation of Parathyroid Hyperplasia in Dialysis Patients
title_full_unstemmed Ultrasonographic Evaluation of Parathyroid Hyperplasia in Dialysis Patients
title_short Ultrasonographic Evaluation of Parathyroid Hyperplasia in Dialysis Patients
title_sort ultrasonographic evaluation of parathyroid hyperplasia in dialysis patients
topic Mini-Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917120/
https://www.ncbi.nlm.nih.gov/pubmed/17173178
http://dx.doi.org/10.1100/tsw.2006.273
work_keys_str_mv AT pavlovicdrasko ultrasonographicevaluationofparathyroidhyperplasiaindialysispatients
AT tomicbrzachrvojka ultrasonographicevaluationofparathyroidhyperplasiaindialysispatients