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Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed
Today's biomedicine builds on the conviction that biochemistry can explain the creation of the body, its anatomy and physiology. Unfortunately there are still deep mysteries strangely “fighting back” when we try to define and understand the organism and its creation in the ontogenesis as emergi...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
TheScientificWorldJOURNAL
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917124/ https://www.ncbi.nlm.nih.gov/pubmed/17072488 http://dx.doi.org/10.1100/tsw.2006.234 |
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author | Ventegodt, Søren Hermansen, Tyge Dahl Flensborg-Madsen, Trine Nielsen, Maj Lyck Clausen, Birgitte Merrick, Joav |
author_facet | Ventegodt, Søren Hermansen, Tyge Dahl Flensborg-Madsen, Trine Nielsen, Maj Lyck Clausen, Birgitte Merrick, Joav |
author_sort | Ventegodt, Søren |
collection | PubMed |
description | Today's biomedicine builds on the conviction that biochemistry can explain the creation of the body, its anatomy and physiology. Unfortunately there are still deep mysteries strangely “fighting back” when we try to define and understand the organism and its creation in the ontogenesis as emerging from biochemistry. In analysing this from a theoretical perspective using a mathematical model focusing on the noise in complex chemical systems we argue that evolving biological structure cannot in principle be a product of chemistry. In this paper we go through the chemical gradient model and argue that this is not able to explain the ontogenesis. We discuss the used gradients as information carriers in chemical self-organizing systems and argue that by use of the “Turing structures” we are only able to modelling the mostly simple biological systems. The bio-chemical model is only able to model simple organization but not to explain the complexity of biological phenomena. We conclude that we seemingly have presented a formal proof (a NO-GO theorem) that the self-organizing chemical systems that are using chemical gradients are not able to explain complex biological matters as the ontogenesis. We need a fundamentally new, information-carrying principle to understand biological information and biological order. |
format | Online Article Text |
id | pubmed-5917124 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | TheScientificWorldJOURNAL |
record_format | MEDLINE/PubMed |
spelling | pubmed-59171242018-06-03 Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed Ventegodt, Søren Hermansen, Tyge Dahl Flensborg-Madsen, Trine Nielsen, Maj Lyck Clausen, Birgitte Merrick, Joav ScientificWorldJournal Review Article Today's biomedicine builds on the conviction that biochemistry can explain the creation of the body, its anatomy and physiology. Unfortunately there are still deep mysteries strangely “fighting back” when we try to define and understand the organism and its creation in the ontogenesis as emerging from biochemistry. In analysing this from a theoretical perspective using a mathematical model focusing on the noise in complex chemical systems we argue that evolving biological structure cannot in principle be a product of chemistry. In this paper we go through the chemical gradient model and argue that this is not able to explain the ontogenesis. We discuss the used gradients as information carriers in chemical self-organizing systems and argue that by use of the “Turing structures” we are only able to modelling the mostly simple biological systems. The bio-chemical model is only able to model simple organization but not to explain the complexity of biological phenomena. We conclude that we seemingly have presented a formal proof (a NO-GO theorem) that the self-organizing chemical systems that are using chemical gradients are not able to explain complex biological matters as the ontogenesis. We need a fundamentally new, information-carrying principle to understand biological information and biological order. TheScientificWorldJOURNAL 2006-10-23 /pmc/articles/PMC5917124/ /pubmed/17072488 http://dx.doi.org/10.1100/tsw.2006.234 Text en Copyright © 2006 Søren Ventegodt et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Review Article Ventegodt, Søren Hermansen, Tyge Dahl Flensborg-Madsen, Trine Nielsen, Maj Lyck Clausen, Birgitte Merrick, Joav Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed |
title | Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed |
title_full | Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed |
title_fullStr | Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed |
title_full_unstemmed | Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed |
title_short | Human Development V: Biochemistry Unable to Explain the Emergence of Biological Form (Morphogenesis) and Therefore a New Principle as Source of Biological Information is Needed |
title_sort | human development v: biochemistry unable to explain the emergence of biological form (morphogenesis) and therefore a new principle as source of biological information is needed |
topic | Review Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917124/ https://www.ncbi.nlm.nih.gov/pubmed/17072488 http://dx.doi.org/10.1100/tsw.2006.234 |
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