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Significant Delay of Lethal Outcome in Cancer Patients Due to Peroral Administration of Bacillus oligonitrophilus KU-1
Treatment of cancer patients remains a serious medical problem and the development of alternative treatment strategies is therefore of great importance. In this connection, we developed a new bacterial-based, anticancer method. Ten cancer patients (three males, seven females) were involved in this s...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
TheScientificWorldJOURNAL
2006
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917170/ https://www.ncbi.nlm.nih.gov/pubmed/17370013 http://dx.doi.org/10.1100/tsw.2006.347 |
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author | Malkov, Sergey V. Markelov, Vladimir V. Polozov, Gleb Y. Barabanschikov, Boris I. Kozhevnikov, Alexander Y. Trushin, Maxim V. |
author_facet | Malkov, Sergey V. Markelov, Vladimir V. Polozov, Gleb Y. Barabanschikov, Boris I. Kozhevnikov, Alexander Y. Trushin, Maxim V. |
author_sort | Malkov, Sergey V. |
collection | PubMed |
description | Treatment of cancer patients remains a serious medical problem and the development of alternative treatment strategies is therefore of great importance. In this connection, we developed a new bacterial-based, anticancer method. Ten cancer patients (three males, seven females) were involved in this study. Bacterial suspension of stationary phase Bacillus oligonitrophilus KU-1 was used as a remedy for peroral administration. In five patients, side effects (sicchasia, slight blood, and intracranial pressure gain) were detected, but all patients showed significant delay of lethal outcome without serious side effects. In conclusion, the suggested method was, in our opinion, a good alternative to conventional chemo- and radiotherapy techniques. In order to evaluate its efficiency for various tumors, a double-blind, placebo-controlled, multicenter study is needed. |
format | Online Article Text |
id | pubmed-5917170 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2006 |
publisher | TheScientificWorldJOURNAL |
record_format | MEDLINE/PubMed |
spelling | pubmed-59171702018-06-03 Significant Delay of Lethal Outcome in Cancer Patients Due to Peroral Administration of Bacillus oligonitrophilus KU-1 Malkov, Sergey V. Markelov, Vladimir V. Polozov, Gleb Y. Barabanschikov, Boris I. Kozhevnikov, Alexander Y. Trushin, Maxim V. ScientificWorldJournal Research Article Treatment of cancer patients remains a serious medical problem and the development of alternative treatment strategies is therefore of great importance. In this connection, we developed a new bacterial-based, anticancer method. Ten cancer patients (three males, seven females) were involved in this study. Bacterial suspension of stationary phase Bacillus oligonitrophilus KU-1 was used as a remedy for peroral administration. In five patients, side effects (sicchasia, slight blood, and intracranial pressure gain) were detected, but all patients showed significant delay of lethal outcome without serious side effects. In conclusion, the suggested method was, in our opinion, a good alternative to conventional chemo- and radiotherapy techniques. In order to evaluate its efficiency for various tumors, a double-blind, placebo-controlled, multicenter study is needed. TheScientificWorldJOURNAL 2006-07-08 /pmc/articles/PMC5917170/ /pubmed/17370013 http://dx.doi.org/10.1100/tsw.2006.347 Text en Copyright © 2006 Sergey V. Malkov et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Malkov, Sergey V. Markelov, Vladimir V. Polozov, Gleb Y. Barabanschikov, Boris I. Kozhevnikov, Alexander Y. Trushin, Maxim V. Significant Delay of Lethal Outcome in Cancer Patients Due to Peroral Administration of Bacillus oligonitrophilus KU-1 |
title | Significant Delay of Lethal Outcome in Cancer Patients Due to Peroral Administration of Bacillus oligonitrophilus KU-1 |
title_full | Significant Delay of Lethal Outcome in Cancer Patients Due to Peroral Administration of Bacillus oligonitrophilus KU-1 |
title_fullStr | Significant Delay of Lethal Outcome in Cancer Patients Due to Peroral Administration of Bacillus oligonitrophilus KU-1 |
title_full_unstemmed | Significant Delay of Lethal Outcome in Cancer Patients Due to Peroral Administration of Bacillus oligonitrophilus KU-1 |
title_short | Significant Delay of Lethal Outcome in Cancer Patients Due to Peroral Administration of Bacillus oligonitrophilus KU-1 |
title_sort | significant delay of lethal outcome in cancer patients due to peroral administration of bacillus oligonitrophilus ku-1 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917170/ https://www.ncbi.nlm.nih.gov/pubmed/17370013 http://dx.doi.org/10.1100/tsw.2006.347 |
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