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Stabilization of a Membrane-Associated Amyloid-β Oligomer for Its Validation in Alzheimer's Disease

We have recently reported on the preparation of a membrane-associated β-barrel Pore-Forming Aβ42 Oligomer (βPFO(Aβ42)). It corresponds to a stable and homogeneous Aβ42 oligomer that inserts into lipid bilayers as a well-defined pore and adopts a specific structure with characteristics of a β-barrel...

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Detalles Bibliográficos
Autores principales:	Serra-Batiste, Montserrat, Tolchard, James, Giusti, Fabrice, Zoonens, Manuela, Carulla, Natàlia
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2018
Materias:	Molecular Biosciences
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917194/ https://www.ncbi.nlm.nih.gov/pubmed/29725595 http://dx.doi.org/10.3389/fmolb.2018.00038

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