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The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer

Non-muscle invasive bladder cancers are a heterogeneous group of cancers whose spectrum includes low grade Ta lesions and high-grade T1 lesions. Accurate staging and grading during initial evaluation and TUR ensures appropriate treatment and prevents the risk of understaging. TUR should be ideally p...

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Detalles Bibliográficos
Autores principales: Nieder, Alan M., Manoharan, Murugesan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2006
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917271/
https://www.ncbi.nlm.nih.gov/pubmed/17619740
http://dx.doi.org/10.1100/tsw.2006.405
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author Nieder, Alan M.
Manoharan, Murugesan
author_facet Nieder, Alan M.
Manoharan, Murugesan
author_sort Nieder, Alan M.
collection PubMed
description Non-muscle invasive bladder cancers are a heterogeneous group of cancers whose spectrum includes low grade Ta lesions and high-grade T1 lesions. Accurate staging and grading during initial evaluation and TUR ensures appropriate treatment and prevents the risk of understaging. TUR should be ideally performed under spinal anesthesia, with a continuous flow video resectoscope to maintain a stable bladder capacity, and a video monitor. The entire bladder must be visualized, with both 30- and 70-degree lenses, and all abnormal areas must be resected, with separate biopsies from each tumor's base. Repeat TUR is recommended for all high grade tumors and T1 tumors, especially if muscle was not present in the initial specimen. Immediate instillation of single dose chemotherapy agents following TUR is highly recommended to reduce the risk of tumor recurrences.
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spelling pubmed-59172712018-06-03 The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer Nieder, Alan M. Manoharan, Murugesan ScientificWorldJournal Review Article Non-muscle invasive bladder cancers are a heterogeneous group of cancers whose spectrum includes low grade Ta lesions and high-grade T1 lesions. Accurate staging and grading during initial evaluation and TUR ensures appropriate treatment and prevents the risk of understaging. TUR should be ideally performed under spinal anesthesia, with a continuous flow video resectoscope to maintain a stable bladder capacity, and a video monitor. The entire bladder must be visualized, with both 30- and 70-degree lenses, and all abnormal areas must be resected, with separate biopsies from each tumor's base. Repeat TUR is recommended for all high grade tumors and T1 tumors, especially if muscle was not present in the initial specimen. Immediate instillation of single dose chemotherapy agents following TUR is highly recommended to reduce the risk of tumor recurrences. TheScientificWorldJOURNAL 2006-07-06 /pmc/articles/PMC5917271/ /pubmed/17619740 http://dx.doi.org/10.1100/tsw.2006.405 Text en Copyright © 2006 Alan M. Nieder and Murugesan Manoharan. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Review Article
Nieder, Alan M.
Manoharan, Murugesan
The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer
title The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer
title_full The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer
title_fullStr The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer
title_full_unstemmed The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer
title_short The Role of the Surgeon and Transurethral Resection in the Treatment of Superficial Bladder Cancer
title_sort role of the surgeon and transurethral resection in the treatment of superficial bladder cancer
topic Review Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917271/
https://www.ncbi.nlm.nih.gov/pubmed/17619740
http://dx.doi.org/10.1100/tsw.2006.405
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