Repeat Intrathecal Triamcinolone Acetonide Application Reduces Acute Occurring Painful Dysesthesia in Patients with Relapsing Remitting Multiple Sclerosis

We describe four patients with relapsing remitting multiple sclerosis (RRMS) who experienced a relapse with acute onset of painful sensations. Pain sensations disappeared in two of them and markedly reduced in the other ones after repeat application of intrathecal triamcinolone acetonide (TCA) follo...

Descripción completa

Detalles Bibliográficos
Autores principales: Hellwig, Kerstin, Lukas, Carsten, Brune, Niels, Hoffmann, Volker, Schimrigk, Sebastian, Przuntek, Horst, Müller, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: TheScientificWorldJOURNAL 2006
Materias:
Case Study
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917289/
https://www.ncbi.nlm.nih.gov/pubmed/16604259
http://dx.doi.org/10.1100/tsw.2006.86
_version_ 1783317176239783936
author Hellwig, Kerstin
Lukas, Carsten
Brune, Niels
Hoffmann, Volker
Schimrigk, Sebastian
Przuntek, Horst
Müller, Thomas
author_facet Hellwig, Kerstin
Lukas, Carsten
Brune, Niels
Hoffmann, Volker
Schimrigk, Sebastian
Przuntek, Horst
Müller, Thomas
author_sort Hellwig, Kerstin
collection PubMed
description We describe four patients with relapsing remitting multiple sclerosis (RRMS) who experienced a relapse with acute onset of painful sensations. Pain sensations disappeared in two of them and markedly reduced in the other ones after repeat application of intrathecal triamcinolone acetonide (TCA) following a prior unsuccessful treatment with intravenous steroids. TCA administration was well tolerated and no serious side effects occurred. Repeated intrathecal TCA injection may provide a substantial benefit in RRMS patients with acute onset of pain due to an inflammatory lesion within the spinal cord.
format Online
Article
Text
id pubmed-5917289
institution National Center for Biotechnology Information
language English
publishDate 2006
publisher TheScientificWorldJOURNAL
record_format MEDLINE/PubMed
spelling pubmed-59172892018-06-03 Repeat Intrathecal Triamcinolone Acetonide Application Reduces Acute Occurring Painful Dysesthesia in Patients with Relapsing Remitting Multiple Sclerosis Hellwig, Kerstin Lukas, Carsten Brune, Niels Hoffmann, Volker Schimrigk, Sebastian Przuntek, Horst Müller, Thomas ScientificWorldJournal Case Study We describe four patients with relapsing remitting multiple sclerosis (RRMS) who experienced a relapse with acute onset of painful sensations. Pain sensations disappeared in two of them and markedly reduced in the other ones after repeat application of intrathecal triamcinolone acetonide (TCA) following a prior unsuccessful treatment with intravenous steroids. TCA administration was well tolerated and no serious side effects occurred. Repeated intrathecal TCA injection may provide a substantial benefit in RRMS patients with acute onset of pain due to an inflammatory lesion within the spinal cord. TheScientificWorldJOURNAL 2006-04-06 /pmc/articles/PMC5917289/ /pubmed/16604259 http://dx.doi.org/10.1100/tsw.2006.86 Text en Copyright © 2006 Kerstin Hellwig et al. https://creativecommons.org/licenses/by/3.0/ This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Case Study
Hellwig, Kerstin
Lukas, Carsten
Brune, Niels
Hoffmann, Volker
Schimrigk, Sebastian
Przuntek, Horst
Müller, Thomas
Repeat Intrathecal Triamcinolone Acetonide Application Reduces Acute Occurring Painful Dysesthesia in Patients with Relapsing Remitting Multiple Sclerosis
title Repeat Intrathecal Triamcinolone Acetonide Application Reduces Acute Occurring Painful Dysesthesia in Patients with Relapsing Remitting Multiple Sclerosis
title_full Repeat Intrathecal Triamcinolone Acetonide Application Reduces Acute Occurring Painful Dysesthesia in Patients with Relapsing Remitting Multiple Sclerosis
title_fullStr Repeat Intrathecal Triamcinolone Acetonide Application Reduces Acute Occurring Painful Dysesthesia in Patients with Relapsing Remitting Multiple Sclerosis
title_full_unstemmed Repeat Intrathecal Triamcinolone Acetonide Application Reduces Acute Occurring Painful Dysesthesia in Patients with Relapsing Remitting Multiple Sclerosis
title_short Repeat Intrathecal Triamcinolone Acetonide Application Reduces Acute Occurring Painful Dysesthesia in Patients with Relapsing Remitting Multiple Sclerosis
title_sort repeat intrathecal triamcinolone acetonide application reduces acute occurring painful dysesthesia in patients with relapsing remitting multiple sclerosis
topic Case Study
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917289/
https://www.ncbi.nlm.nih.gov/pubmed/16604259
http://dx.doi.org/10.1100/tsw.2006.86
work_keys_str_mv AT hellwigkerstin repeatintrathecaltriamcinoloneacetonideapplicationreducesacuteoccurringpainfuldysesthesiainpatientswithrelapsingremittingmultiplesclerosis
AT lukascarsten repeatintrathecaltriamcinoloneacetonideapplicationreducesacuteoccurringpainfuldysesthesiainpatientswithrelapsingremittingmultiplesclerosis
AT bruneniels repeatintrathecaltriamcinoloneacetonideapplicationreducesacuteoccurringpainfuldysesthesiainpatientswithrelapsingremittingmultiplesclerosis
AT hoffmannvolker repeatintrathecaltriamcinoloneacetonideapplicationreducesacuteoccurringpainfuldysesthesiainpatientswithrelapsingremittingmultiplesclerosis
AT schimrigksebastian repeatintrathecaltriamcinoloneacetonideapplicationreducesacuteoccurringpainfuldysesthesiainpatientswithrelapsingremittingmultiplesclerosis
AT przuntekhorst repeatintrathecaltriamcinoloneacetonideapplicationreducesacuteoccurringpainfuldysesthesiainpatientswithrelapsingremittingmultiplesclerosis
AT mullerthomas repeatintrathecaltriamcinoloneacetonideapplicationreducesacuteoccurringpainfuldysesthesiainpatientswithrelapsingremittingmultiplesclerosis

Ejemplares similares