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Polyclonal Antibodies to DNA Modified with 4‐Nitroquinoline 1‐Oxide: Application for the Detection of 4‐Nitroquinoline 1‐Oxide‐DNA Adducts in vivo

Antibodies against 4‐nitroquinoline 1‐oxide (4NQO) adducts were elicited in rabbits immunized with 4NQO‐modified DNA complexed with methylated bovine serum albumin. In enzymelinked immunosorbent assay (ELISA), the antibodies could recognize either denatured or native 4NQO‐modified DNA, but not unmod...

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Detalles Bibliográficos
Autores principales: Morita, Toshiteru, Ikeda, Sachiya, Minoura, Yasushi, Kojima, Misaki, Tada, Mariko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917454/
https://www.ncbi.nlm.nih.gov/pubmed/3130354
http://dx.doi.org/10.1111/j.1349-7006.1988.tb01577.x

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