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Polyclonal Antibodies to DNA Modified with 4‐Nitroquinoline 1‐Oxide: Application for the Detection of 4‐Nitroquinoline 1‐Oxide‐DNA Adducts in vivo
Antibodies against 4‐nitroquinoline 1‐oxide (4NQO) adducts were elicited in rabbits immunized with 4NQO‐modified DNA complexed with methylated bovine serum albumin. In enzymelinked immunosorbent assay (ELISA), the antibodies could recognize either denatured or native 4NQO‐modified DNA, but not unmod...
Autores principales: | Morita, Toshiteru, Ikeda, Sachiya, Minoura, Yasushi, Kojima, Misaki, Tada, Mariko |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1988
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917454/ https://www.ncbi.nlm.nih.gov/pubmed/3130354 http://dx.doi.org/10.1111/j.1349-7006.1988.tb01577.x |
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