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Rostrocaudal Areal Patterning of Human PSC-Derived Cortical Neurons by FGF8 Signaling

The cerebral cortex is subdivided into distinct areas that have particular functions. The rostrocaudal (R-C) gradient of fibroblast growth factor 8 (FGF8) signaling defines this areal identity during neural development. In this study, we recapitulated cortical R-C patterning in human pluripotent ste...

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Detalles Bibliográficos
Autores principales: Imaizumi, Kent, Fujimori, Koki, Ishii, Seiji, Otomo, Asako, Hosoi, Yasushi, Miyajima, Hiroaki, Warita, Hitoshi, Aoki, Masashi, Hadano, Shinji, Akamatsu, Wado, Okano, Hideyuki
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Society for Neuroscience 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917473/
https://www.ncbi.nlm.nih.gov/pubmed/29707616
http://dx.doi.org/10.1523/ENEURO.0368-17.2018