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Specific Reduction of Toxic Side Effects of Adriamycin by Induction of Metallothionein in Mice

The effect of preinduction of metallothionein (MT) by bismuth (Bi) compounds on the toxic side effects and antitumor activity of adriamycin (ADR) was investigated in mice. Preinduction of MT by oral administration of bismuth subnitrate (BSN) significantly decreased the lethal toxicity, cardiotoxicit...

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Detalles Bibliográficos
Autores principales:	Naganuma, Akira, Satoh, Masahiko, Imura, Nobumasa
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1988
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917480/ https://www.ncbi.nlm.nih.gov/pubmed/3131288 http://dx.doi.org/10.1111/j.1349-7006.1988.tb01605.x

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