APPEARANCE OF ANTIBODIES AGAINST PHOSPHOTYROSINE AND TYROSINE PHOSPHORYLATION OF LYMPHOCYTE PROTEINS IN HUMAN T CELL LEUKEMIA VIRUS TYPE‐I INFECTION

Antibodies reactive with O‐phosphotyrosine (Ptyr) were detected in all of 56 patients with adult T cell leukemia (ATL) with high titers ranging from 1:1,600 to 1:25,000 in 91% of the patients, whereas 97% of 70 healthy subjects showed titers of 1:400 or less. Ptyr‐containing proteins (molecular weig...

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Detalles Bibliográficos
Autores principales: Ogawa, Ryoichi, Koizumi, Tamio, Nakao, Yoshinobu, Sakitani, Mitsuru, Watanabe, Yasushi, Fujita, Takuo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917482/
https://www.ncbi.nlm.nih.gov/pubmed/2453495
http://dx.doi.org/10.1111/j.1349-7006.1988.tb01589.x
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author Ogawa, Ryoichi
Koizumi, Tamio
Nakao, Yoshinobu
Sakitani, Mitsuru
Watanabe, Yasushi
Fujita, Takuo
author_facet Ogawa, Ryoichi
Koizumi, Tamio
Nakao, Yoshinobu
Sakitani, Mitsuru
Watanabe, Yasushi
Fujita, Takuo
author_sort Ogawa, Ryoichi
collection PubMed
description Antibodies reactive with O‐phosphotyrosine (Ptyr) were detected in all of 56 patients with adult T cell leukemia (ATL) with high titers ranging from 1:1,600 to 1:25,000 in 91% of the patients, whereas 97% of 70 healthy subjects showed titers of 1:400 or less. Ptyr‐containing proteins (molecular weights of 70k, 45k and 30k) were detected in peripheral lymphocytes from patients with ATL. These proteins might be involved as antigens in the induction of such antibodies.
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spelling pubmed-59174822018-05-11 APPEARANCE OF ANTIBODIES AGAINST PHOSPHOTYROSINE AND TYROSINE PHOSPHORYLATION OF LYMPHOCYTE PROTEINS IN HUMAN T CELL LEUKEMIA VIRUS TYPE‐I INFECTION Ogawa, Ryoichi Koizumi, Tamio Nakao, Yoshinobu Sakitani, Mitsuru Watanabe, Yasushi Fujita, Takuo Jpn J Cancer Res Rapid Communication Antibodies reactive with O‐phosphotyrosine (Ptyr) were detected in all of 56 patients with adult T cell leukemia (ATL) with high titers ranging from 1:1,600 to 1:25,000 in 91% of the patients, whereas 97% of 70 healthy subjects showed titers of 1:400 or less. Ptyr‐containing proteins (molecular weights of 70k, 45k and 30k) were detected in peripheral lymphocytes from patients with ATL. These proteins might be involved as antigens in the induction of such antibodies. Blackwell Publishing Ltd 1988-03 /pmc/articles/PMC5917482/ /pubmed/2453495 http://dx.doi.org/10.1111/j.1349-7006.1988.tb01589.x Text en
spellingShingle Rapid Communication
Ogawa, Ryoichi
Koizumi, Tamio
Nakao, Yoshinobu
Sakitani, Mitsuru
Watanabe, Yasushi
Fujita, Takuo
APPEARANCE OF ANTIBODIES AGAINST PHOSPHOTYROSINE AND TYROSINE PHOSPHORYLATION OF LYMPHOCYTE PROTEINS IN HUMAN T CELL LEUKEMIA VIRUS TYPE‐I INFECTION
title APPEARANCE OF ANTIBODIES AGAINST PHOSPHOTYROSINE AND TYROSINE PHOSPHORYLATION OF LYMPHOCYTE PROTEINS IN HUMAN T CELL LEUKEMIA VIRUS TYPE‐I INFECTION
title_full APPEARANCE OF ANTIBODIES AGAINST PHOSPHOTYROSINE AND TYROSINE PHOSPHORYLATION OF LYMPHOCYTE PROTEINS IN HUMAN T CELL LEUKEMIA VIRUS TYPE‐I INFECTION
title_fullStr APPEARANCE OF ANTIBODIES AGAINST PHOSPHOTYROSINE AND TYROSINE PHOSPHORYLATION OF LYMPHOCYTE PROTEINS IN HUMAN T CELL LEUKEMIA VIRUS TYPE‐I INFECTION
title_full_unstemmed APPEARANCE OF ANTIBODIES AGAINST PHOSPHOTYROSINE AND TYROSINE PHOSPHORYLATION OF LYMPHOCYTE PROTEINS IN HUMAN T CELL LEUKEMIA VIRUS TYPE‐I INFECTION
title_short APPEARANCE OF ANTIBODIES AGAINST PHOSPHOTYROSINE AND TYROSINE PHOSPHORYLATION OF LYMPHOCYTE PROTEINS IN HUMAN T CELL LEUKEMIA VIRUS TYPE‐I INFECTION
title_sort appearance of antibodies against phosphotyrosine and tyrosine phosphorylation of lymphocyte proteins in human t cell leukemia virus type‐i infection
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917482/
https://www.ncbi.nlm.nih.gov/pubmed/2453495
http://dx.doi.org/10.1111/j.1349-7006.1988.tb01589.x
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