DEFECTIVE HUMAN IMMUNO‐DEFICIENCY VIRUS (HIV) PARTICLES PRODUCED BY CLONED CELLS OF HTLV‐I‐CARRYING MT‐4 CELLS PERSISTENTLY INFECTED WITH HIV

Persistently HIV‐infected cell lines were isolated from surviving and proliferating cells after infection of HTLV‐I‐carrying MT‐4 cells with cell‐free human immunodeficiency virus (HIV); HTLV‐IIIB and LAV. The media of the cloned cell cultures did not cause HIV infection of MT‐4, MOLT‐4, TALL‐1, or...

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Detalles Bibliográficos
Autores principales: Ikuta, Kazuyoshi, Morita, Chizuko, Nakai, Masuyo, Yamamoto, Naoki, Kato, Shiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917499/
https://www.ncbi.nlm.nih.gov/pubmed/2898463
http://dx.doi.org/10.1111/j.1349-7006.1988.tb01607.x
Descripción
Sumario:Persistently HIV‐infected cell lines were isolated from surviving and proliferating cells after infection of HTLV‐I‐carrying MT‐4 cells with cell‐free human immunodeficiency virus (HIV); HTLV‐IIIB and LAV. The media of the cloned cell cultures did not cause HIV infection of MT‐4, MOLT‐4, TALL‐1, or HL‐60 cells. Most of the constituents of the virus in the media were env proteins and many defective doughnut‐shaped particles released from the cells were identified by electron microscopy.

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