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WIDE‐SPECTRUM INITIATION MODELS: POSSIBLE APPLICATIONS TO MEDIUM‐TERM MULTIPLE ORGAN BIOASSAYS FOR CARCINOGENESIS MODIFIERS

Two wide‐spectrum initiation models were investigated in F344 male rats. Model I: After sequential treatment with diethylnitrosamine (DEN), N‐methylnitrosourea (MNU) and dihydroxy‐di‐N‐propylnitrosamine (DHPN), animals were given phenobarbital (PB) or N, N‐dibutylnitrosamine (DBN) as a test compound...

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Detalles Bibliográficos
Autores principales:	Ito, Nobuyuki, Imaida, Katsumi, Tsuda, Hiroyuki, Shibata, Masa‐aki, Aoki, Toyohiko, de Camargo, Joao Lauro V., Fukushima, Shoji
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Blackwell Publishing Ltd 1988
Materias:	Rapid Communication
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917503/ https://www.ncbi.nlm.nih.gov/pubmed/3133331 http://dx.doi.org/10.1111/j.1349-7006.1988.tb01606.x

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