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Pharmacokinetic Approach to Rational Therapeutic Doses for Human Tumor‐bearing Nude Mice

To improve clinical predictability from therapeutic results of various antitnmor agents in human tumor/nude mouse models it seems to be important to use a dose pharmacokinetically equivalent to the clinical dose. Thus, we attempted to find the dose of a given drug that can reproduce in the nude mous...

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Detalles Bibliográficos
Autores principales: Inaba, Makoto, Kobayashi, Tomowo, Tashiro, Tazuko, Sakurai, Yoshio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917508/
https://www.ncbi.nlm.nih.gov/pubmed/3133339
http://dx.doi.org/10.1111/j.1349-7006.1988.tb01620.x