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Pharmacokinetic Approach to Rational Therapeutic Doses for Human Tumor‐bearing Nude Mice
To improve clinical predictability from therapeutic results of various antitnmor agents in human tumor/nude mouse models it seems to be important to use a dose pharmacokinetically equivalent to the clinical dose. Thus, we attempted to find the dose of a given drug that can reproduce in the nude mous...
Autores principales: | , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1988
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917508/ https://www.ncbi.nlm.nih.gov/pubmed/3133339 http://dx.doi.org/10.1111/j.1349-7006.1988.tb01620.x |