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Combined Use of α‐Difluoromethylornithine and an Inhibitor of S‐Adenosylmethionine Decarboxylase in Mice Bearing P388 Leukemia or Lewis Lung Carcinoma

The antitumor and antimetastatic effects of α‐difluoromethylornithine (DFMO), an inhibitor of ornithine decarboxylase, combined with an inhibitor of S‐adenosylmethionine decarboxylase, either methylglyoxal bis(guanylhydrazone) (MGBG) or ethylglyoxal bis(guanylhydrazone) (EGBG), were studied in mice...

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Detalles Bibliográficos
Autores principales: Nakaike, Shiro, Kashiwagi, Keiko, Terao, Kiyoshi, Iio, Kokoro, Igarashi, Kazuei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917513/
https://www.ncbi.nlm.nih.gov/pubmed/3133338
http://dx.doi.org/10.1111/j.1349-7006.1988.tb01619.x