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Dentinogenic ghost cell tumor: Tumor in the garb of a cyst!

The dentinogenic ghost cell tumor (DGCT) is a relatively uncommon locally invasive neoplasm that mimics several inflammatory/reactive lesions of the gingiva or odontogenic cysts. The confirmatory diagnosis of this rare lesion can only be made with histopathological examination. Routine staining reve...

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Autores principales: Korranne, Vaishali, Merchant, Yash, Joshi, Samir, Halli, Rajshekhar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Medknow Publications & Media Pvt Ltd 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917534/
https://www.ncbi.nlm.nih.gov/pubmed/29731583
http://dx.doi.org/10.4103/jomfp.JOMFP_144_16
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author Korranne, Vaishali
Merchant, Yash
Joshi, Samir
Halli, Rajshekhar
author_facet Korranne, Vaishali
Merchant, Yash
Joshi, Samir
Halli, Rajshekhar
author_sort Korranne, Vaishali
collection PubMed
description The dentinogenic ghost cell tumor (DGCT) is a relatively uncommon locally invasive neoplasm that mimics several inflammatory/reactive lesions of the gingiva or odontogenic cysts. The confirmatory diagnosis of this rare lesion can only be made with histopathological examination. Routine staining reveals features of a “mixed” tumor as ghost cells with calcification, dysplastic dentin and islands of epithelium in rosette pattern in mature connective tissue are visible. The case report describes an asymptomatic growth in the maxillary gingiva of a young patient that was incidentally diagnosed as a DGCT after biopsy. Malignant transformation of this lesion to its more aggressive counterpart, odontogenic ghost cell carcinoma has been described, and hence, regular follow-up of diagnosed cases is imperative. The purpose of the paper is to report a case that adds to the literature and this will consequently help to diagnose and understand the biological behavior of these lesions better.
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spelling pubmed-59175342018-05-04 Dentinogenic ghost cell tumor: Tumor in the garb of a cyst! Korranne, Vaishali Merchant, Yash Joshi, Samir Halli, Rajshekhar J Oral Maxillofac Pathol Case Report The dentinogenic ghost cell tumor (DGCT) is a relatively uncommon locally invasive neoplasm that mimics several inflammatory/reactive lesions of the gingiva or odontogenic cysts. The confirmatory diagnosis of this rare lesion can only be made with histopathological examination. Routine staining reveals features of a “mixed” tumor as ghost cells with calcification, dysplastic dentin and islands of epithelium in rosette pattern in mature connective tissue are visible. The case report describes an asymptomatic growth in the maxillary gingiva of a young patient that was incidentally diagnosed as a DGCT after biopsy. Malignant transformation of this lesion to its more aggressive counterpart, odontogenic ghost cell carcinoma has been described, and hence, regular follow-up of diagnosed cases is imperative. The purpose of the paper is to report a case that adds to the literature and this will consequently help to diagnose and understand the biological behavior of these lesions better. Medknow Publications & Media Pvt Ltd 2018 /pmc/articles/PMC5917534/ /pubmed/29731583 http://dx.doi.org/10.4103/jomfp.JOMFP_144_16 Text en Copyright: © 2018 Journal of Oral and Maxillofacial Pathology http://creativecommons.org/licenses/by-nc-sa/4.0 This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Case Report
Korranne, Vaishali
Merchant, Yash
Joshi, Samir
Halli, Rajshekhar
Dentinogenic ghost cell tumor: Tumor in the garb of a cyst!
title Dentinogenic ghost cell tumor: Tumor in the garb of a cyst!
title_full Dentinogenic ghost cell tumor: Tumor in the garb of a cyst!
title_fullStr Dentinogenic ghost cell tumor: Tumor in the garb of a cyst!
title_full_unstemmed Dentinogenic ghost cell tumor: Tumor in the garb of a cyst!
title_short Dentinogenic ghost cell tumor: Tumor in the garb of a cyst!
title_sort dentinogenic ghost cell tumor: tumor in the garb of a cyst!
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917534/
https://www.ncbi.nlm.nih.gov/pubmed/29731583
http://dx.doi.org/10.4103/jomfp.JOMFP_144_16
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