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EXPRESSION OF PARATHYROID HORMONE‐RELATED PROTEIN mRNA IN TUMORS OBTAINED FROM PATIENTS WITH HUMORAL HYPERCALCEMIA OF MALIGNANCY
Human parathyroid hormone‐related protein (PTHrP) mRNA was detected in all fresh cancer tissues consecutively obtained from 6 patients with humoral hypercalcemia of malignancy (HHM). The primary sites of the cancers in these cases were distributed among different organs including the lung, esophagus...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Blackwell Publishing Ltd
1988
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917578/ https://www.ncbi.nlm.nih.gov/pubmed/3137193 http://dx.doi.org/10.1111/j.1349-7006.1988.tb02221.x |
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author | Honda, Satoshi Yamaguchi, Ken Suzuki, Masafumi Sato, Yutaka Adachi, Isamu Kimura, Satoshi Abe, Kaoru |
author_facet | Honda, Satoshi Yamaguchi, Ken Suzuki, Masafumi Sato, Yutaka Adachi, Isamu Kimura, Satoshi Abe, Kaoru |
author_sort | Honda, Satoshi |
collection | PubMed |
description | Human parathyroid hormone‐related protein (PTHrP) mRNA was detected in all fresh cancer tissues consecutively obtained from 6 patients with humoral hypercalcemia of malignancy (HHM). The primary sites of the cancers in these cases were distributed among different organs including the lung, esophagus, kidney and ovary. PTHrP mRNA was undetectable in all 10 fresh cancer tissues obtained from normocalcemic patients. These results suggest PTHrP as a major cause of HHM. |
format | Online Article Text |
id | pubmed-5917578 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 1988 |
publisher | Blackwell Publishing Ltd |
record_format | MEDLINE/PubMed |
spelling | pubmed-59175782018-05-11 EXPRESSION OF PARATHYROID HORMONE‐RELATED PROTEIN mRNA IN TUMORS OBTAINED FROM PATIENTS WITH HUMORAL HYPERCALCEMIA OF MALIGNANCY Honda, Satoshi Yamaguchi, Ken Suzuki, Masafumi Sato, Yutaka Adachi, Isamu Kimura, Satoshi Abe, Kaoru Jpn J Cancer Res Rapid Communication Human parathyroid hormone‐related protein (PTHrP) mRNA was detected in all fresh cancer tissues consecutively obtained from 6 patients with humoral hypercalcemia of malignancy (HHM). The primary sites of the cancers in these cases were distributed among different organs including the lung, esophagus, kidney and ovary. PTHrP mRNA was undetectable in all 10 fresh cancer tissues obtained from normocalcemic patients. These results suggest PTHrP as a major cause of HHM. Blackwell Publishing Ltd 1988-06 /pmc/articles/PMC5917578/ /pubmed/3137193 http://dx.doi.org/10.1111/j.1349-7006.1988.tb02221.x Text en |
spellingShingle | Rapid Communication Honda, Satoshi Yamaguchi, Ken Suzuki, Masafumi Sato, Yutaka Adachi, Isamu Kimura, Satoshi Abe, Kaoru EXPRESSION OF PARATHYROID HORMONE‐RELATED PROTEIN mRNA IN TUMORS OBTAINED FROM PATIENTS WITH HUMORAL HYPERCALCEMIA OF MALIGNANCY |
title | EXPRESSION OF PARATHYROID HORMONE‐RELATED PROTEIN mRNA IN TUMORS OBTAINED FROM PATIENTS WITH HUMORAL HYPERCALCEMIA OF MALIGNANCY |
title_full | EXPRESSION OF PARATHYROID HORMONE‐RELATED PROTEIN mRNA IN TUMORS OBTAINED FROM PATIENTS WITH HUMORAL HYPERCALCEMIA OF MALIGNANCY |
title_fullStr | EXPRESSION OF PARATHYROID HORMONE‐RELATED PROTEIN mRNA IN TUMORS OBTAINED FROM PATIENTS WITH HUMORAL HYPERCALCEMIA OF MALIGNANCY |
title_full_unstemmed | EXPRESSION OF PARATHYROID HORMONE‐RELATED PROTEIN mRNA IN TUMORS OBTAINED FROM PATIENTS WITH HUMORAL HYPERCALCEMIA OF MALIGNANCY |
title_short | EXPRESSION OF PARATHYROID HORMONE‐RELATED PROTEIN mRNA IN TUMORS OBTAINED FROM PATIENTS WITH HUMORAL HYPERCALCEMIA OF MALIGNANCY |
title_sort | expression of parathyroid hormone‐related protein mrna in tumors obtained from patients with humoral hypercalcemia of malignancy |
topic | Rapid Communication |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917578/ https://www.ncbi.nlm.nih.gov/pubmed/3137193 http://dx.doi.org/10.1111/j.1349-7006.1988.tb02221.x |
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