A MONOCLONAL ANTIBODY THAT RECOGNIZES A COMMON ANTIGEN IN MYELOID AND HUMAN T‐CELL LEUKEMIA VIRUS TYPE I‐CARRYING CELLS

A novel monoclonal antibody, designated D‐213, was generated to human myeloid cell line PL‐21. D‐213 defined a 47‐kD antigen which was specifically expressed in normal and leukemic cells of the myeloid lineage and in T‐cell lines carrying human T‐cell leukemia virus type I. This antibody was also re...

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Detalles Bibliográficos
Autores principales: Takeuchi, Tamotsu, Kubonishi, Ichiro, Takahashi, Kiyoshi, Ohtsuki, Yuji, Taguchi, Hirokuni, Miyoshi, Isao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917591/
https://www.ncbi.nlm.nih.gov/pubmed/3139595
http://dx.doi.org/10.1111/j.1349-7006.1988.tb00040.x
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author Takeuchi, Tamotsu
Kubonishi, Ichiro
Takahashi, Kiyoshi
Ohtsuki, Yuji
Taguchi, Hirokuni
Miyoshi, Isao
author_facet Takeuchi, Tamotsu
Kubonishi, Ichiro
Takahashi, Kiyoshi
Ohtsuki, Yuji
Taguchi, Hirokuni
Miyoshi, Isao
author_sort Takeuchi, Tamotsu
collection PubMed
description A novel monoclonal antibody, designated D‐213, was generated to human myeloid cell line PL‐21. D‐213 defined a 47‐kD antigen which was specifically expressed in normal and leukemic cells of the myeloid lineage and in T‐cell lines carrying human T‐cell leukemia virus type I. This antibody was also reactive with adult T‐cell leukemia/lymphoma (ATLL) cells in formalin‐fixed, paraffin‐embedded tissues. D‐213 would be useful for making an immunohistochemical diagnosis of ATLL in cases where serological or virological information is not available.
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spelling pubmed-59175912018-05-11 A MONOCLONAL ANTIBODY THAT RECOGNIZES A COMMON ANTIGEN IN MYELOID AND HUMAN T‐CELL LEUKEMIA VIRUS TYPE I‐CARRYING CELLS Takeuchi, Tamotsu Kubonishi, Ichiro Takahashi, Kiyoshi Ohtsuki, Yuji Taguchi, Hirokuni Miyoshi, Isao Jpn J Cancer Res Rapid Communication A novel monoclonal antibody, designated D‐213, was generated to human myeloid cell line PL‐21. D‐213 defined a 47‐kD antigen which was specifically expressed in normal and leukemic cells of the myeloid lineage and in T‐cell lines carrying human T‐cell leukemia virus type I. This antibody was also reactive with adult T‐cell leukemia/lymphoma (ATLL) cells in formalin‐fixed, paraffin‐embedded tissues. D‐213 would be useful for making an immunohistochemical diagnosis of ATLL in cases where serological or virological information is not available. Blackwell Publishing Ltd 1988-07 /pmc/articles/PMC5917591/ /pubmed/3139595 http://dx.doi.org/10.1111/j.1349-7006.1988.tb00040.x Text en
spellingShingle Rapid Communication
Takeuchi, Tamotsu
Kubonishi, Ichiro
Takahashi, Kiyoshi
Ohtsuki, Yuji
Taguchi, Hirokuni
Miyoshi, Isao
A MONOCLONAL ANTIBODY THAT RECOGNIZES A COMMON ANTIGEN IN MYELOID AND HUMAN T‐CELL LEUKEMIA VIRUS TYPE I‐CARRYING CELLS
title A MONOCLONAL ANTIBODY THAT RECOGNIZES A COMMON ANTIGEN IN MYELOID AND HUMAN T‐CELL LEUKEMIA VIRUS TYPE I‐CARRYING CELLS
title_full A MONOCLONAL ANTIBODY THAT RECOGNIZES A COMMON ANTIGEN IN MYELOID AND HUMAN T‐CELL LEUKEMIA VIRUS TYPE I‐CARRYING CELLS
title_fullStr A MONOCLONAL ANTIBODY THAT RECOGNIZES A COMMON ANTIGEN IN MYELOID AND HUMAN T‐CELL LEUKEMIA VIRUS TYPE I‐CARRYING CELLS
title_full_unstemmed A MONOCLONAL ANTIBODY THAT RECOGNIZES A COMMON ANTIGEN IN MYELOID AND HUMAN T‐CELL LEUKEMIA VIRUS TYPE I‐CARRYING CELLS
title_short A MONOCLONAL ANTIBODY THAT RECOGNIZES A COMMON ANTIGEN IN MYELOID AND HUMAN T‐CELL LEUKEMIA VIRUS TYPE I‐CARRYING CELLS
title_sort monoclonal antibody that recognizes a common antigen in myeloid and human t‐cell leukemia virus type i‐carrying cells
topic Rapid Communication
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917591/
https://www.ncbi.nlm.nih.gov/pubmed/3139595
http://dx.doi.org/10.1111/j.1349-7006.1988.tb00040.x
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