A SYNTHETIC ADJUVANT EFFECTIVE IN INDUCING ANTITUMOR IMMUNITY

Guinea pigs which were injected repeatedly with a mixture of a 3MKC1 extract of line 10 tumor and 6‐O‐(2‐tetradecyl‐hexadecanoyl)‐muramyl‐dipeptide (B30‐MDP) rejected a tumor graft of line 10. Such an adjuvant effect of B30‐MDP was also demonstrated when X‐ray‐treated line 10 cells were mixed with B...

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Detalles Bibliográficos
Autores principales: Kataoka, Tetsuro, Tokunaga, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917595/
https://www.ncbi.nlm.nih.gov/pubmed/3139596
http://dx.doi.org/10.1111/j.1349-7006.1988.tb00042.x
Descripción
Sumario:Guinea pigs which were injected repeatedly with a mixture of a 3MKC1 extract of line 10 tumor and 6‐O‐(2‐tetradecyl‐hexadecanoyl)‐muramyl‐dipeptide (B30‐MDP) rejected a tumor graft of line 10. Such an adjuvant effect of B30‐MDP was also demonstrated when X‐ray‐treated line 10 cells were mixed with B30‐MDP dissolved in phosphatebuffered saline and inoculated into the animals.

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