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Mechanisms of Differential Strain Sensitivity in Gastric Carcinogenesis

The genetically‐controlled, distinct sensitivity of different rat strains to N‐methyl‐N′‐nitro‐N‐nitrosoguanidine (MNNG)‐induced cancer of the glandular stomach and duodenum was investigated. MNNG is activated through thiols, and the thiol content of the glandular stomach, duodenum, and liver of the...

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Detalles Bibliográficos
Autores principales: Weisburger, John H., Jones, R. Conrad, Barnes, William S., Pegg, Anthony E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1988
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917662/
https://www.ncbi.nlm.nih.gov/pubmed/3148600
http://dx.doi.org/10.1111/j.1349-7006.1988.tb01560.x