Inhibition of Intracellular Bleomycin Hydrolase Activity by E‐64 Leads to the Potentiation of the Cytotoxicity of Peplomycin against Chinese Hamster Lung Cells

N‐(N‐(L‐3‐frans‐carboxyoxiran‐2‐carbonyl)‐L‐leucyl)‐agmatine (E‐64), a thiol protease inhibitor, potentiated the cytotoxicity of peplomycin against the Chinese hamster lung (V79) cell. After the treatment of the cells with E‐64 (50 μg/ml) for 12 h, bleomycin hydrolasc activity of the cells was almos...

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Detalles Bibliográficos
Autores principales: Nishimura, Chiaki, Nishimura, Toshio, Tanaka, Nobuo, Yamaguchi, Hideyo, Suzuki, Hideo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917688/
https://www.ncbi.nlm.nih.gov/pubmed/2468632
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02246.x

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917688/
https://www.ncbi.nlm.nih.gov/pubmed/2468632
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02246.x

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