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Inhibition of Intracellular Bleomycin Hydrolase Activity by E‐64 Leads to the Potentiation of the Cytotoxicity of Peplomycin against Chinese Hamster Lung Cells
N‐(N‐(L‐3‐frans‐carboxyoxiran‐2‐carbonyl)‐L‐leucyl)‐agmatine (E‐64), a thiol protease inhibitor, potentiated the cytotoxicity of peplomycin against the Chinese hamster lung (V79) cell. After the treatment of the cells with E‐64 (50 μg/ml) for 12 h, bleomycin hydrolasc activity of the cells was almos...
| Autores principales: | , , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Blackwell Publishing Ltd
1989
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917688/ https://www.ncbi.nlm.nih.gov/pubmed/2468632 http://dx.doi.org/10.1111/j.1349-7006.1989.tb02246.x |