Proliferative Cell Index in Endometrial Adenocarcinoma of Different Nuclear Grades

Proliferative cell indices (PCI) in 20 cases of endometrial adenocarcinoma were obtained by staining DNA polymerase α. The PCI ranged from 11.1 to 42.1, averaging 24.7±8.7. Four cases of stage III all exhibited fairly large PCI (30.4–32.9). In contrast, in 16 cases of stage I the values were spread...

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Autores principales: Mushika, Masafumi, Shibata, Kanemitsu, Miwa, Tadashi, Suzuoki, Yozo, Kaneda, Tsuguhiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917718/
https://www.ncbi.nlm.nih.gov/pubmed/2470714
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02296.x
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author Mushika, Masafumi
Shibata, Kanemitsu
Miwa, Tadashi
Suzuoki, Yozo
Kaneda, Tsuguhiro
author_facet Mushika, Masafumi
Shibata, Kanemitsu
Miwa, Tadashi
Suzuoki, Yozo
Kaneda, Tsuguhiro
author_sort Mushika, Masafumi
collection PubMed
description Proliferative cell indices (PCI) in 20 cases of endometrial adenocarcinoma were obtained by staining DNA polymerase α. The PCI ranged from 11.1 to 42.1, averaging 24.7±8.7. Four cases of stage III all exhibited fairly large PCI (30.4–32.9). In contrast, in 16 cases of stage I the values were spread over a wide range. In 13 cases with histological grade (HG) 1 of stage I, larger PCI were obtained in the nuclear grade (NG) 2 group; the mean PCI values of HG 1‐NG 1 and HG 1‐NG 2 were 16.5 ±4.6 and 25.6±5.2, respectively. Because of the good correlation between PCI and HG or NG, PCI may be useful as an additional prognostic factor in endometrial adenocarcinoma, especially in stage I cases.
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spelling pubmed-59177182018-05-11 Proliferative Cell Index in Endometrial Adenocarcinoma of Different Nuclear Grades Mushika, Masafumi Shibata, Kanemitsu Miwa, Tadashi Suzuoki, Yozo Kaneda, Tsuguhiro Jpn J Cancer Res Article Proliferative cell indices (PCI) in 20 cases of endometrial adenocarcinoma were obtained by staining DNA polymerase α. The PCI ranged from 11.1 to 42.1, averaging 24.7±8.7. Four cases of stage III all exhibited fairly large PCI (30.4–32.9). In contrast, in 16 cases of stage I the values were spread over a wide range. In 13 cases with histological grade (HG) 1 of stage I, larger PCI were obtained in the nuclear grade (NG) 2 group; the mean PCI values of HG 1‐NG 1 and HG 1‐NG 2 were 16.5 ±4.6 and 25.6±5.2, respectively. Because of the good correlation between PCI and HG or NG, PCI may be useful as an additional prognostic factor in endometrial adenocarcinoma, especially in stage I cases. Blackwell Publishing Ltd 1989-03 /pmc/articles/PMC5917718/ /pubmed/2470714 http://dx.doi.org/10.1111/j.1349-7006.1989.tb02296.x Text en
spellingShingle Article
Mushika, Masafumi
Shibata, Kanemitsu
Miwa, Tadashi
Suzuoki, Yozo
Kaneda, Tsuguhiro
Proliferative Cell Index in Endometrial Adenocarcinoma of Different Nuclear Grades
title Proliferative Cell Index in Endometrial Adenocarcinoma of Different Nuclear Grades
title_full Proliferative Cell Index in Endometrial Adenocarcinoma of Different Nuclear Grades
title_fullStr Proliferative Cell Index in Endometrial Adenocarcinoma of Different Nuclear Grades
title_full_unstemmed Proliferative Cell Index in Endometrial Adenocarcinoma of Different Nuclear Grades
title_short Proliferative Cell Index in Endometrial Adenocarcinoma of Different Nuclear Grades
title_sort proliferative cell index in endometrial adenocarcinoma of different nuclear grades
topic Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917718/
https://www.ncbi.nlm.nih.gov/pubmed/2470714
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02296.x
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AT suzuokiyozo proliferativecellindexinendometrialadenocarcinomaofdifferentnucleargrades
AT kanedatsuguhiro proliferativecellindexinendometrialadenocarcinomaofdifferentnucleargrades

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