Adult T‐cell Leukemia in Spouses

A married couple who developed adult T‐cell leukemia (ATL) is described. The husband presented with acute ATL and died soon after admission in spite of aggressive chemotherapy, and his wife, who is diagnosed as smoldering ATL, has been followed in the out‐patient clinic. The couple had serum antibod...

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Detalles Bibliográficos
Autores principales: Sanada, Isao, Yamaguchi, Kazunari, Yoshida, Mitsuaki, Ishii, Toshinori, Tsukamoto, Atsuko, Sato, Masahiko, Obata, Shin‐ichiro, Shido, Tadahiro
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Blackwell Publishing Ltd 1989
Materias:
Rapid Communication
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917751/
https://www.ncbi.nlm.nih.gov/pubmed/2502513
http://dx.doi.org/10.1111/j.1349-7006.1989.tb02326.x
Descripción
Sumario:A married couple who developed adult T‐cell leukemia (ATL) is described. The husband presented with acute ATL and died soon after admission in spite of aggressive chemotherapy, and his wife, who is diagnosed as smoldering ATL, has been followed in the out‐patient clinic. The couple had serum antibodies against human T‐cell leukemia virus type I (MTLV‐I) and the monoclonal integration of HTLV‐I proviral DNA in their lymphocytes. The patients described represent the first reported example of ATL in a married couple.

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