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The snowball effect of RNA binding protein dysfunction in amyotrophic lateral sclerosis

This scientific commentary refers to ‘TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis’, by Deshaies et al. (doi:10.1093/brain/awy062).

Detalles Bibliográficos
Autores principales: Fratta, Pietro, Isaacs, Adrian M
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917769/
https://www.ncbi.nlm.nih.gov/pubmed/29701791
http://dx.doi.org/10.1093/brain/awy091
Descripción
Sumario:This scientific commentary refers to ‘TDP-43 regulates the alternative splicing of hnRNP A1 to yield an aggregation-prone variant in amyotrophic lateral sclerosis’, by Deshaies et al. (doi:10.1093/brain/awy062).