Aberrant Epigenetic Gene Regulation in GABAergic Interneuron Subpopulations in the Hippocampal Dentate Gyrus of Mouse Offspring Following Developmental Exposure to Hexachlorophene

Maternal hexachlorophene (HCP) exposure causes transient disruption of hippocampal neurogenesis in mouse offspring. We examined epigenetically hypermethylated and downregulated genes related to this HCP-induced disrupted neurogenesis. Mated female mice were dietary exposed to 0 or 100 ppm HCP from g...

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Detalles Bibliográficos
Autores principales: Watanabe, Yousuke, Abe, Hajime, Nakajima, Kota, Ideta-Otsuka, Maky, Igarashi, Katsuhide, Woo, Gye-Hyeong, Yoshida, Toshinori, Shibutani, Makoto
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2018
Materias:
Hexachlorophene and Epigenetic Alterations in Hippocampus
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5917777/
https://www.ncbi.nlm.nih.gov/pubmed/29301063
http://dx.doi.org/10.1093/toxsci/kfx291

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